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Snrk SNF related kinase [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36579, updated on 4-Jan-2025

Summary

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Official Symbol
Snrkprovided by FlyBase
Official Full Name
SNF related kinaseprovided by FlyBase
Primary source
FLYBASE:FBgn0033915
Locus tag
Dmel_CG8485
See related
AllianceGenome:FB:FBgn0033915
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
152964_at; CG8485; Dmel\CG8485; SNRK
Summary
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Orthologous to human SNRK (SNF related kinase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Snrk in Genome Data Viewer
Location:
50E4-50E4; 2-69 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14235787..14239703, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10123292..10127208, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Optic atrophy 1 Neighboring gene mir-1016 stem loop Neighboring gene Ubiquitin specific protease 20/33 Neighboring gene SET and MYND domain containing, arthropod-specific, member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization. Couderc JL, et al. PLoS One, 2017. PMID 28767695, Free PMC Article
  2. A screen for selective killing of cells with chromosomal instability induced by a spindle checkpoint defect. Shaukat Z, et al. PLoS One, 2012. PMID 23077619, Free PMC Article
  3. Cytoplasmic polyadenylation is a major mRNA regulator during oogenesis and egg activation in Drosophila. Cui J, et al. Dev Biol, 2013 Nov 1. PMID 23978535, Free PMC Article
  4. The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis. McMillan EA, et al. J Biol Chem, 2018 Feb 23. PMID 29326167, Free PMC Article
  5. Gepoclu: a software tool for identifying and analyzing gene positional clusters in large-scale gene expression analysis. Dottorini T, et al. BMC Bioinformatics, 2011 Jan 26. PMID 21269436, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
SNF related kinase
Names
CG8485-PA
CG8485-PB
CG8485-PC
Snrk-PA
Snrk-PB
Snrk-PC
NP_610942.2
NP_725370.1
NP_725371.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    14235787..14239703 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137098.3 → NP_610942.2  SNF related kinase, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610942.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E981, Q8SWX3
    Related
    FBpp0086695
    Conserved Domains (3) summary
    smart00220
    Location:20 → 273
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14339
    Location:296 → 338
    UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
    cd14074
    Location:16 → 273
    STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase

  2. NM_166041.2 → NP_725370.1  SNF related kinase, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725370.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E981, Q8SWX3
    Related
    FBpp0086697
    Conserved Domains (3) summary
    smart00220
    Location:20 → 273
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14339
    Location:296 → 338
    UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
    cd14074
    Location:16 → 273
    STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase

  3. NM_166042.2 → NP_725371.1  SNF related kinase, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725371.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q0E981, Q8SWX3
    Related
    FBpp0086698
    Conserved Domains (3) summary
    smart00220
    Location:20 → 273
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14339
    Location:296 → 338
    UBA_SNRK; UBA domain of SNF-related serine/threonine-protein kinase (SNRK) and similar proteins mainly found in metazoa
    cd14074
    Location:16 → 273
    STKc_SNRK; Catalytic domain of the Serine/Threonine Kinase, SNF1-related kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0E981 Q0E981
Q8SWX3 Q8SWX3
Q960G5 Q960G5

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