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CG18327 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36567, updated on 4-Jan-2025

Summary

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Official Symbol
CG18327provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033904
Locus tag
Dmel_CG18327
See related
AllianceGenome:FB:FBgn0033904
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG18327
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial transmembrane transport. Predicted to be located in mitochondrial inner membrane. Orthologous to several human genes including SLC25A35 (solute carrier family 25 member 35). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG18327 in Genome Data Viewer
Location:
50E1-50E1; 2-69 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14166982..14168233)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10054487..10055738)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase 1 Neighboring gene eukaryotic translation initiation factor 3 subunit m Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44368 Neighboring gene uncharacterized protein Neighboring gene Receptor expression enhancing protein B Neighboring gene mitochondrial ribosomal protein S16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Environmental complexity and the purging of deleterious alleles. Singh A, et al. Evolution, 2017 Nov. PMID 28840604
  2. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
  3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
  4. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article
  5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial transmembrane transport TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG18327-PA
CG18327-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    14166982..14168233
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_137090.2 → NP_610934.1  uncharacterized protein Dmel_CG18327, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610934.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z9L9, Q4QQ90
    Related
    FBpp0086651
    Conserved Domains (2) summary
    PTZ00169
    Location:5 → 293
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:204 → 296
    Mito_carr; Mitochondrial carrier protein

  2. NM_001274037.1 → NP_001260966.1  uncharacterized protein Dmel_CG18327, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260966.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z9L9, Q4QQ90
    Conserved Domains (2) summary
    PTZ00169
    Location:5 → 293
    PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
    pfam00153
    Location:204 → 296
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z9L9 A1Z9L9

Gene LinkOut

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