U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Asphd2 aspartate beta-hydroxylase domain containing 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 364948, updated on 27-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
Asphd2provided by RGD
Official Full Name
aspartate beta-hydroxylase domain containing 2provided by RGD
Primary source
RGD:1306020
See related
EnsemblRapid:ENSRNOG00000061004 AllianceGenome:RGD:1306020
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306020
Summary
Predicted to enable dioxygenase activity and metal ion binding activity. Predicted to be located in membrane. Orthologous to human ASPHD2 (aspartate beta-hydroxylase domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 45.9) See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Asphd2 in Genome Data Viewer
Location:
12q16
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (49908539..49919060)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (44248132..44258653)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (50269347..50279855)

Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene myosin XVIIIb Neighboring gene U6 spliceosomal RNA Neighboring gene seizure related 6 homolog like Neighboring gene coiled-coil domain containing 121 like 2 Neighboring gene coiled-coil domain-containing protein 121-like Neighboring gene HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 Neighboring gene tuftelin interacting protein 11 Neighboring gene SRR1 domain containing

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC105590

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables dioxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
aspartate beta-hydroxylase domain-containing protein 2
Names
3110001L23Rik
calsequestrin-binding protein
NP_001009716.1
XP_008767573.1
XP_017453903.1
XP_017453904.1
XP_017453905.1
XP_017453906.1
XP_038945577.1
XP_038945579.1
XP_038945580.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009716.2 → NP_001009716.1  aspartate beta-hydroxylase domain-containing protein 2

    See identical proteins and their annotated locations for NP_001009716.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000012
    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086030.1 Reference GRCr8

    Range
    49908539..49919060
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017598414.3 → XP_017453903.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

  2. XM_017598415.3 → XP_017453904.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

  3. XM_017598417.3 → XP_017453906.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Related
    ENSRNOP00000068694.1, ENSRNOT00000079190.3
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

  4. XM_039089652.2 → XP_038945580.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

  5. XM_017598416.3 → XP_017453905.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

  6. XM_039089651.2 → XP_038945579.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

  7. XM_008769351.4 → XP_008767573.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    See identical proteins and their annotated locations for XP_008767573.1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase

  8. XM_039089649.2 → XP_038945577.1  aspartate beta-hydroxylase domain-containing protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q5HZW3
    UniProtKB/TrEMBL
    A6J258
    Conserved Domains (1) summary
    pfam05118
    Location:166 → 325
    Asp_Arg_Hydrox; Aspartyl/Asparaginyl beta-hydroxylase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5HZW3.1 GenPept UniProtKB/Swiss-Prot:Q5HZW3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools