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sca - scabrous

Involved in several processes, including chaeta morphogenesis; imaginal disc-derived wing margin morphogenesis; and ommatidial rotation. Predicted to be active in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including epithelial cell; epithelium; ganglia; imaginal disc; and somatic precursor cell. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; brain ischemia; diabetic retinopathy; familial hypobetalipoproteinemia 2; and hereditary angioedema. Orthologous to several human genes including ANGPT1 (angiopoietin 1); ANGPT2 (angiopoietin 2); and ANGPT4 (angiopoietin 4). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to sca

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Species Gene Architecture aa