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CG8785 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36391, updated on 4-Jan-2025

Summary

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Official Symbol
CG8785provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033760
Locus tag
Dmel_CG8785
See related
AllianceGenome:FB:FBgn0033760
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8785
Summary
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be active in vacuolar membrane. Is expressed in adult abdomen; adult head; adult thorax; embryonic midgut chamber; and embryonic/larval midgut. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See CG8785 in Genome Data Viewer
Location:
49B10-49B11; 2-67 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12640690..12648224, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8528195..8535729, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene spt4 Neighboring gene Mevalonate kinase Neighboring gene Imitation SWI Neighboring gene uncharacterized protein Neighboring gene Zinc transporter 49B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparative neuroanatomy and genomics of hugin and pheromone biosynthesis activating neuropeptide (PBAN). Bader R, et al. Fly (Austin), 2007 Jul-Aug. PMID 18820431
  2. Molecular Basis for Cephalic Mechanosensitivity of Drosophila Larvae. Zhang Z, et al. Neurosci Bull, 2020 Sep. PMID 32761438, Free PMC Article
  3. Differential amino acid transporter expression in adult Drosophila melanogaster tissues. Wright Y, et al. MicroPubl Biol, 2024. PMID 38481556, Free PMC Article
  4. The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila. Landis GN, et al. Aging (Albany NY), 2015 Jan. PMID 25614682, Free PMC Article
  5. Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster. Whitaker R, et al. Aging (Albany NY), 2014 May. PMID 24864304, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables amino acid transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid transmembrane transport ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
is_active_in vacuolar membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8785-PA
CG8785-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12640690..12648224 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136960.3 → NP_610804.1  uncharacterized protein Dmel_CG8785, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610804.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K2W3
    Related
    FBpp0086994
    Conserved Domains (2) summary
    COG0814
    Location:60 → 457
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:62 → 463
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

  2. NM_165932.2 → NP_725205.1  uncharacterized protein Dmel_CG8785, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_725205.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K2W3
    Related
    FBpp0086995
    Conserved Domains (2) summary
    COG0814
    Location:60 → 457
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:62 → 463
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K2W3 Q7K2W3

Gene LinkOut

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