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CG8834 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36356, updated on 4-Jan-2025

Summary

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Official Symbol
CG8834provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033733
Locus tag
Dmel_CG8834
See related
AllianceGenome:FB:FBgn0033733
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG8834; mdcds_23070
Summary
Predicted to enable long-chain fatty acid-CoA ligase activity. Predicted to be involved in fatty-acyl-CoA biosynthetic process and long-chain fatty acid metabolic process. Is expressed in adult head. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG8834 in Genome Data Viewer
Location:
49A4-49A4; 2-67 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12420475..12422535, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8307316..8310040, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Deoxyribose-phosphate aldolase Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Firefly luciferase: an adenylate-forming enzyme for multicatalytic functions. Inouye S. Cell Mol Life Sci, 2010 Feb. PMID 19859663, Free PMC Article
  2. Characterization of CG6178 gene product with high sequence similarity to firefly luciferase in Drosophila melanogaster. Oba Y, et al. Gene, 2004 Mar 31. PMID 15033536
  3. Identifying Loci Contributing to Natural Variation in Xenobiotic Resistance in Drosophila. Najarro MA, et al. PLoS Genet, 2015 Nov. PMID 26619284, Free PMC Article
  4. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase. Oba Y, et al. Biosci Biotechnol Biochem, 2005 Apr. PMID 15849423
  5. Survival Rate and Transcriptional Response upon Infection with the Generalist Parasite Beauveria bassiana in a World-Wide Sample of Drosophila melanogaster. Paparazzo F, et al. PLoS One, 2015. PMID 26154519, Free PMC Article

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables long-chain fatty acid-CoA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in fatty-acyl-CoA biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in long-chain fatty acid metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG8834-PA
NP_610779.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    12420475..12422535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136935.2 → NP_610779.1  uncharacterized protein Dmel_CG8834 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610779.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z8Z9, C1C3H7
    Related
    FBpp0087065
    Conserved Domains (2) summary
    COG0318
    Location:20 → 529
    CaiC; Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]
    cl17068
    Location:46 → 519
    AFD_class_I; Adenylate forming domain, Class I superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z8Z9 A1Z8Z9

Gene LinkOut

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