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Mslnl mesothelin-like [ Rattus norvegicus (Norway rat) ]

Gene ID: 363554, updated on 2-Nov-2024

Summary

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Official Symbol
Mslnlprovided by RGD
Official Full Name
mesothelin-likeprovided by RGD
Primary source
RGD:1561732
See related
EnsemblRapid:ENSRNOG00000039339 AllianceGenome:RGD:1561732
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1561732
Summary
Predicted to be involved in cell-matrix adhesion. Predicted to be located in membrane. Predicted to be active in cell surface. Orthologous to human MSLNL (mesothelin like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 5.1), Brain (RPKM 3.8) and 9 other tissues See more
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Genomic context

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See Mslnl in Genome Data Viewer
Location:
10q12
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (15260084..15276190)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (14755344..14771673)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15103047..15119427)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene G protein subunit gamma 13 Neighboring gene chromosome transmission fidelity factor 18 Neighboring gene RNA pseudouridine synthase domain containing 1 Neighboring gene mesothelin Neighboring gene cytosolic iron-sulfur assembly component 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mesothelin-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    15260084..15276190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063270020.1 → XP_063126090.1  mesothelin-like protein isoform X1

  2. XM_008767615.4 → XP_008765837.1  mesothelin-like protein isoform X2

    See identical proteins and their annotated locations for XP_008765837.1

    UniProtKB/TrEMBL
    D4AB62
    Related
    ENSRNOP00000057036.3, ENSRNOT00000060286.5
    Conserved Domains (1) summary
    pfam06060
    Location:1 → 584
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)

  3. XM_039087109.2 → XP_038943037.1  mesothelin-like protein isoform X3

    Conserved Domains (1) summary
    pfam06060
    Location:1 → 379
    Mesothelin; Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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