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Fbxl6 F-box and leucine-rich repeat protein 6 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362941, updated on 4-Jan-2025

Summary

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Official Symbol
Fbxl6provided by RGD
Official Full Name
F-box and leucine-rich repeat protein 6provided by RGD
Primary source
RGD:1359687
See related
EnsemblRapid:ENSRNOG00000025497 AllianceGenome:RGD:1359687
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Orthologous to human FBXL6 (F-box and leucine rich repeat protein 6). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Adrenal (RPKM 68.4), Kidney (RPKM 58.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Fbxl6 in Genome Data Viewer
Location:
7q34
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (110140243..110143176, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (108259097..108262528, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (117602056..117604954, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 52 member 2 Neighboring gene transfer RNA proline (anticodon AGG) 52 Neighboring gene transmembrane protein 249 Neighboring gene uncharacterized LOC134479929 Neighboring gene uncharacterized LOC134479928

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Identification of a family of human F-box proteins. Cenciarelli C, et al. Curr Biol, 1999 Oct 21. PMID 10531035
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC95310

General protein information

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Preferred Names
F-box/LRR-repeat protein 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005563.1 → NP_001005563.1  F-box/LRR-repeat protein 6

    See identical proteins and their annotated locations for NP_001005563.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082108
    UniProtKB/TrEMBL
    A0A8I6G6V1, A6HSA6, F7FE66, Q641W5
    Related
    ENSRNOP00000035719.3, ENSRNOT00000035199.6
    Conserved Domains (3) summary
    cd09293
    Location:171 → 390
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:188 → 213
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:105 → 155
    F-box-like; F-box-like

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    110140243..110143176 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039079548.2 → XP_038935476.1  F-box/LRR-repeat protein 6 isoform X2

    Conserved Domains (3) summary
    cd09293
    Location:207 → 323
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:188 → 213
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:105 → 152
    F-box-like

  2. XM_039079549.2 → XP_038935477.1  F-box/LRR-repeat protein 6 isoform X3

    UniProtKB/TrEMBL
    A6HSA7
    Conserved Domains (2) summary
    cd09293
    Location:118 → 269
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:35 → 60
    LRR_AMN1; leucine-rich repeat [structural motif]

  3. XM_039079547.2 → XP_038935475.1  F-box/LRR-repeat protein 6 isoform X1

    Conserved Domains (3) summary
    cd09293
    Location:207 → 327
    AMN1; Antagonist of mitotic exit network protein 1
    sd00034
    Location:188 → 213
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam12937
    Location:105 → 152
    F-box-like
Nucleotide Protein Strain
Heading Accession and Version

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