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Lin52 lin-52 DREAM MuvB core complex component [ Rattus norvegicus (Norway rat) ]

Gene ID: 362763, updated on 27-Nov-2024

Summary

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Official Symbol
Lin52provided by RGD
Official Full Name
lin-52 DREAM MuvB core complex componentprovided by RGD
Primary source
RGD:1306798
See related
EnsemblRapid:ENSRNOG00000043441 AllianceGenome:RGD:1306798
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306798
Summary
Predicted to be involved in regulation of DNA-templated transcription. Predicted to be part of DRM complex. Orthologous to human LIN52 (lin-52 DREAM MuvB core complex component). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Kidney (RPKM 72.2), Brain (RPKM 68.6) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Lin52 in Genome Data Viewer
Location:
6q31
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (109829896..109927122)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (104098818..104199323)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (108167412..108264459)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene basal body orientation factor 1 Neighboring gene ring finger protein 113A2 Neighboring gene aldehyde dehydrogenase 6 family, member A1 Neighboring gene visual system homeobox 2 Neighboring gene ATP binding cassette subfamily D member 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of DRM complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein lin-52 homolog
Names
lin-52 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001398854.1 → NP_001385783.1  protein lin-52 homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    Related
    ENSRNOP00000105493.1, ENSRNOT00000166526.1

  2. NM_001398855.1 → NP_001385784.1  protein lin-52 homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000006
    Related
    ENSRNOP00000061629.3, ENSRNOT00000064426.5

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    109829896..109927122
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006240356.5 → XP_006240418.1  protein lin-52 homolog isoform X1

    See identical proteins and their annotated locations for XP_006240418.1

    Conserved Domains (1) summary
    pfam10044
    Location:18 → 100
    LIN52; Retinal tissue protein

  2. XM_063262122.1 → XP_063118192.1  protein lin-52 homolog isoform X8

  3. XM_017594487.3 → XP_017449976.1  protein lin-52 homolog isoform X2

    Related
    ENSRNOP00000104334.1, ENSRNOT00000133031.1

  4. XM_017594488.3 → XP_017449977.1  protein lin-52 homolog isoform X3

    Related
    ENSRNOP00000104915.1, ENSRNOT00000161805.1

  5. XM_008764889.4 → XP_008763111.1  protein lin-52 homolog isoform X5

    See identical proteins and their annotated locations for XP_008763111.1

    Related
    ENSRNOP00000112655.1, ENSRNOT00000151317.1
    Conserved Domains (1) summary
    pfam10044
    Location:18 → 100
    LIN52; Retinal tissue protein

  6. XM_006240358.5 → XP_006240420.1  protein lin-52 homolog isoform X4

    See identical proteins and their annotated locations for XP_006240420.1

    UniProtKB/TrEMBL
    A0A8I6GAV2
    Related
    ENSRNOP00000084676.2, ENSRNOT00000104563.2
    Conserved Domains (1) summary
    pfam10044
    Location:18 → 118
    LIN52; Retinal tissue protein

  7. XM_008764890.4 → XP_008763112.1  protein lin-52 homolog isoform X6

    See identical proteins and their annotated locations for XP_008763112.1

    Conserved Domains (1) summary
    pfam10044
    Location:18 → 98
    LIN52; Retinal tissue protein

  8. XM_063262121.1 → XP_063118191.1  protein lin-52 homolog isoform X7

RNA

  1. XR_354978.5 RNA Sequence

  2. XR_001838493.3 RNA Sequence

  3. XR_010052121.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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