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Gpn2 GPN-loop GTPase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362614, updated on 27-Nov-2024

Summary

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Official Symbol
Gpn2provided by RGD
Official Full Name
GPN-loop GTPase 2provided by RGD
Primary source
RGD:1311749
See related
EnsemblRapid:ENSRNOG00000007083 AllianceGenome:RGD:1311749
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Atpbd1b; RGD1311749
Summary
Predicted to enable GTPase activity. Orthologous to human GPN2 (GPN-loop GTPase 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Thymus (RPKM 69.2), Adrenal (RPKM 60.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Gpn2 in Genome Data Viewer
Location:
5q36
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (151093279..151101114)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (145809455..145817252)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (151806458..151813954)

Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL29-like Neighboring gene nuclear receptor subfamily 0, group B, member 2 Neighboring gene G patch domain containing 3 Neighboring gene zinc finger DHHC-type palmitoyltransferase 18 Neighboring gene stratifin Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, et al. Nature, 2004 Apr 1. PMID 15057822
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
GPN-loop GTPase 2
Names
ATP-binding domain 1 family member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270959.1 → NP_001257888.1  GPN-loop GTPase 2

    See identical proteins and their annotated locations for NP_001257888.1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000005
    UniProtKB/Swiss-Prot
    D4A7C0
    Related
    ENSRNOP00000009275.4, ENSRNOT00000009275.9
    Conserved Domains (2) summary
    COG1100
    Location:13 → 182
    Gem1; GTPase SAR1 family domain [General function prediction only]
    pfam03029
    Location:14 → 261
    ATP_bind_1; Conserved hypothetical ATP binding protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086023.1 Reference GRCr8

    Range
    151093279..151101114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039110392.2 → XP_038966320.1  GPN-loop GTPase 2 isoform X1

    Conserved Domains (1) summary
    cl38936
    Location:27 → 148
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
D4A7C0.1 GenPept UniProtKB/Swiss-Prot:D4A7C0

Gene LinkOut

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