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Golt1b golgi transport 1B [ Rattus norvegicus (Norway rat) ]

Gene ID: 362460, updated on 4-Jan-2025

Summary

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Official Symbol
Golt1bprovided by RGD
Official Full Name
golgi transport 1Bprovided by RGD
Primary source
RGD:1310691
See related
EnsemblRapid:ENSRNOG00000058386 AllianceGenome:RGD:1310691
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310691
Summary
Predicted to be involved in positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum and membrane. Orthologous to human GOLT1B (golgi transport 1B). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 128.3), Lung (RPKM 123.5) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Golt1b in Genome Data Viewer
Location:
4q44
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (177064071..177077165)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (175333056..175346156)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (176606669..176617884)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102549024 Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene RecQ like helicase Neighboring gene spexin hormone Neighboring gene glycogen synthase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. ZMPSTE24 defends against influenza and other pathogenic viruses. Fu B, et al. J Exp Med, 2017 Apr 3. PMID 28246125, Free PMC Article
  2. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Matsuda A, et al. Oncogene, 2003 May 22. PMID 12761501
  3. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
  
involved_in positive regulation of canonical NF-kappaB signal transduction ISO
Inferred from Sequence Orthology
more info
 PubMed 
involved_in retrograde transport, endosome to Golgi IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
vesicle transport protein GOT1B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001113783.1 → NP_001107255.1  vesicle transport protein GOT1B

    See identical proteins and their annotated locations for NP_001107255.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158751
    UniProtKB/TrEMBL
    A6IMT9, B0BNB0
    Related
    ENSRNOP00000092199.1, ENSRNOT00000108416.2
    Conserved Domains (1) summary
    cl02130
    Location:4 → 120
    Got1; Got1/Sft2-like family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    177064071..177077165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039107915.2 → XP_038963843.1  vesicle transport protein GOT1B isoform X3

  2. XM_063286374.1 → XP_063142444.1  vesicle transport protein GOT1B isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZME6, A6IMT9

  3. XM_039107914.2 → XP_038963842.1  vesicle transport protein GOT1B isoform X2

    UniProtKB/TrEMBL
    A6IMT9
    Related
    ENSRNOP00000070214.3, ENSRNOT00000084700.3
    Conserved Domains (1) summary
    cl02130
    Location:4 → 120
    Got1; Got1/Sft2-like family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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