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Zfp637 zinc finger protein 637 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362425, updated on 4-Jan-2025

Summary

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Official Symbol
Zfp637provided by RGD
Official Full Name
zinc finger protein 637provided by RGD
Primary source
RGD:1559850
See related
EnsemblRapid:ENSRNOG00000023065 AllianceGenome:RGD:1559850
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
AZF1; DZF11
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF32 (zinc finger protein 32). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 141.3), Thymus (RPKM 105.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Zfp637 in Genome Data Viewer
Location:
4q42
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (152656937..152682499)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (150984940..151010079)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (149857127..149882828)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene enolase 1, pseudogene 20 Neighboring gene uncharacterized LOC120102373 Neighboring gene uncharacterized LOC120102374 Neighboring gene zinc finger protein 239 Neighboring gene uncharacterized LOC134486838

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. A novel profile of expressed sequence tags for zinc finger encoding genes from the poorly differentiated exocrine pancreatic cell line AR4IP. Gebelein B, et al. Cancer Lett, 1996 Aug 2. PMID 8697448
  2. Identification and characterization of zinc finger encoding genes from the tumoral exocrine pancreatic cell line AR42J. Mesa K, et al. Cancer Lett, 1996 Jun 5. PMID 8635150
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
zinc finger protein 32
Names
zinc finger protein 1
zinc finger protein 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134908.1 → NP_001128380.1  zinc finger protein 32

    See identical proteins and their annotated locations for NP_001128380.1

    Status: PROVISIONAL

    Source sequence(s)
    BC158822
    UniProtKB/TrEMBL
    B0BNH4
    Related
    ENSRNOP00000101511.1, ENSRNOT00000154102.1
    Conserved Domains (3) summary
    COG5048
    Location:39 → 236
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:78 → 98
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:118 → 143
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    152656937..152682499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006237193.5 → XP_006237255.1  zinc finger protein 32 isoform X2

    Related
    ENSRNOP00000087762.2, ENSRNOT00000104853.2
    Conserved Domains (3) summary
    COG5048
    Location:150 → 347
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:189 → 209
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:229 → 254
    zf-H2C2_2; Zinc-finger double domain

  2. XM_063286311.1 → XP_063142381.1  zinc finger protein 32 isoform X7

  3. XM_063286312.1 → XP_063142382.1  zinc finger protein 32 isoform X8

    UniProtKB/TrEMBL
    A0A8I6AKD8

  4. XM_063286320.1 → XP_063142390.1  zinc finger protein 32 isoform X16

  5. XM_063286308.1 → XP_063142378.1  zinc finger protein 32 isoform X4

    UniProtKB/TrEMBL
    A0A8I6A6H3

  6. XM_063286317.1 → XP_063142387.1  zinc finger protein 32 isoform X13

  7. XM_063286313.1 → XP_063142383.1  zinc finger protein 32 isoform X9

  8. XM_063286318.1 → XP_063142388.1  zinc finger protein 32 isoform X14

  9. XM_063286307.1 → XP_063142377.1  zinc finger protein 32 isoform X1

  10. XM_063286314.1 → XP_063142384.1  zinc finger protein 32 isoform X10

  11. XM_063286315.1 → XP_063142385.1  zinc finger protein 32 isoform X11

  12. XM_063286310.1 → XP_063142380.1  zinc finger protein 32 isoform X6

    Related
    ENSRNOP00000094186.2, ENSRNOT00000105993.2

  13. XM_039107865.2 → XP_038963793.1  zinc finger protein 32 isoform X3

    Conserved Domains (2) summary
    COG5048
    Location:138 → 335
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:177 → 197
    ZF_C2H2; C2H2 Zn finger [structural motif]

  14. XM_063286309.1 → XP_063142379.1  zinc finger protein 32 isoform X5

  15. XM_063286319.1 → XP_063142389.1  zinc finger protein 32 isoform X15

    UniProtKB/TrEMBL
    A6IL38

  16. XM_063286316.1 → XP_063142386.1  zinc finger protein 32 isoform X12

    UniProtKB/TrEMBL
    B0BNH4

RNA

  1. XR_010065678.1 RNA Sequence

  2. XR_010065677.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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