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Tmbim7 transmembrane BAX inhibitor motif containing 7 [ Rattus norvegicus (Norway rat) ]

Gene ID: 362319, updated on 27-Nov-2024

Summary

Official Symbol
Tmbim7provided by RGD
Official Full Name
transmembrane BAX inhibitor motif containing 7provided by RGD
Primary source
RGD:1306626
See related
EnsemblRapid:ENSRNOG00000008585 AllianceGenome:RGD:1306626
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306626
Summary
Predicted to enable calcium channel activity. Predicted to be active in Golgi apparatus and membrane. Orthologous to human TMBIM7P (transmembrane BAX inhibitor motif containing 7, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 399.8) See more
Orthologs
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Genomic context

See Tmbim7 in Genome Data Viewer
Location:
4q13
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (31421371..31454319, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (30466651..30499565, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (27606049..27639025, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486560 Neighboring gene KRIT1, ankyrin repeat containing Neighboring gene ankyrin repeat and IBR domain containing 1 Neighboring gene DND microRNA-mediated repression inhibitor 1, pseudogene 2 Neighboring gene GATA zinc finger domain containing 1 Neighboring gene peroxisomal biogenesis factor 1

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Clone Names

  • MGC125025

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039612.2NP_001034701.2  bax inhibitor 1-like

    See identical proteins and their annotated locations for NP_001034701.2

    Status: VALIDATED

    Source sequence(s)
    BC105862
    UniProtKB/TrEMBL
    A6K281, F1LS63, Q3KR74
    Related
    ENSRNOP00000011377.6, ENSRNOT00000011377.7
    Conserved Domains (1) summary
    cd10428
    Location:85302
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    31421371..31454319 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006236047.5XP_006236109.1  bax inhibitor 1-like isoform X1

    UniProtKB/TrEMBL
    Q3KR74
    Conserved Domains (1) summary
    cd10428
    Location:85272
    LFG_like; Proteins similar to and including lifeguard (LFG), a putative regulator of apoptosis