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Ssbp2 single-stranded DNA binding protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361877, updated on 4-Jan-2025

Summary

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Official Symbol
Ssbp2provided by RGD
Official Full Name
single-stranded DNA binding protein 2provided by RGD
Primary source
RGD:1562968
See related
EnsemblRapid:ENSRNOG00000016213 AllianceGenome:RGD:1562968
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562968
Summary
Predicted to enable single-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human SSBP2 (single stranded DNA binding protein 2). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Brain (RPKM 158.2), Heart (RPKM 65.1) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Ssbp2 in Genome Data Viewer
Location:
2q12
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (24385494..24673768)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (22650488..22938669)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (20416795..20707838)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134485571 Neighboring gene uncharacterized LOC134485570 Neighboring gene uncharacterized LOC120100665 Neighboring gene uncharacterized LOC103691419 Neighboring gene transfer RNA leucine (anticodon AAG) 15 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene acyl-CoA thioesterase 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
single-stranded DNA-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399027.1 → NP_001385956.1  single-stranded DNA-binding protein 2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    F1M3J3
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:99 → 355
    SSDP; Single-stranded DNA binding protein, SSDP

  2. NM_001399028.1 → NP_001385957.1  single-stranded DNA-binding protein 2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I6AA81, A0A8I6ALH6
    Related
    ENSRNOP00000094798.2, ENSRNOT00000109181.2
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:83 → 346
    SSDP; Single-stranded DNA binding protein, SSDP

  3. NM_001399029.1 → NP_001385958.1  single-stranded DNA-binding protein 2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    F1M3J3
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:83 → 339
    SSDP; Single-stranded DNA binding protein, SSDP

  4. NM_001399030.1 → NP_001385959.1  single-stranded DNA-binding protein 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    F1M3J3
    Related
    ENSRNOP00000112474.1, ENSRNOT00000137293.1
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:83 → 338
    SSDP; Single-stranded DNA binding protein, SSDP

  5. NM_001399031.1 → NP_001385960.1  single-stranded DNA-binding protein 2 isoform 5

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    F1M3J3

  6. NM_001399032.1 → NP_001385961.1  single-stranded DNA-binding protein 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I6AA81
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:92 → 309
    SSDP; Single-stranded DNA binding protein, SSDP

  7. NM_001399033.1 → NP_001385962.1  single-stranded DNA-binding protein 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I6AA81
    Related
    ENSRNOP00000104531.1, ENSRNOT00000153761.1
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:92 → 308
    SSDP; Single-stranded DNA binding protein, SSDP

  8. NM_001399034.1 → NP_001385963.1  single-stranded DNA-binding protein 2 isoform 8

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I6AA81, A0A8I6GBJ4
    Related
    ENSRNOP00000103552.1, ENSRNOT00000151109.1

  9. NM_001399035.1 → NP_001385964.1  single-stranded DNA-binding protein 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    A0A8I6ACS5
    Related
    ENSRNOP00000106335.1, ENSRNOT00000147077.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    24385494..24673768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063282020.1 → XP_063138090.1  single-stranded DNA-binding protein 2 isoform X33

  2. XM_063282022.1 → XP_063138092.1  single-stranded DNA-binding protein 2 isoform X34

    UniProtKB/TrEMBL
    A6I4P6

  3. XM_039103448.2 → XP_038959376.1  single-stranded DNA-binding protein 2 isoform X31

    Conserved Domains (1) summary
    pfam04503
    Location:19 → 272
    SSDP; Single-stranded DNA binding protein, SSDP

  4. XM_063282003.1 → XP_063138073.1  single-stranded DNA-binding protein 2 isoform X2

  5. XM_039103427.2 → XP_038959355.1  single-stranded DNA-binding protein 2 isoform X3

    Conserved Domains (2) summary
    smart00667
    Location:80 → 108
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:162 → 425
    SSDP; Single-stranded DNA binding protein, SSDP

  6. XM_039103428.2 → XP_038959356.1  single-stranded DNA-binding protein 2 isoform X4

    Conserved Domains (2) summary
    smart00667
    Location:80 → 108
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:162 → 418
    SSDP; Single-stranded DNA binding protein, SSDP

  7. XM_039103429.2 → XP_038959357.1  single-stranded DNA-binding protein 2 isoform X5

    Conserved Domains (2) summary
    smart00667
    Location:80 → 108
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:162 → 417
    SSDP; Single-stranded DNA binding protein, SSDP

  8. XM_063282006.1 → XP_063138076.1  single-stranded DNA-binding protein 2 isoform X10

  9. XM_063282007.1 → XP_063138077.1  single-stranded DNA-binding protein 2 isoform X11

  10. XM_039103430.2 → XP_038959358.1  single-stranded DNA-binding protein 2 isoform X12

    Conserved Domains (2) summary
    smart00667
    Location:80 → 108
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:171 → 388
    SSDP; Single-stranded DNA binding protein, SSDP

  11. XM_063282008.1 → XP_063138078.1  single-stranded DNA-binding protein 2 isoform X13

  12. XM_008760646.4 → XP_008758868.2  single-stranded DNA-binding protein 2 isoform X6

  13. XM_063282004.1 → XP_063138074.1  single-stranded DNA-binding protein 2 isoform X7

  14. XM_008760648.4 → XP_008758870.2  single-stranded DNA-binding protein 2 isoform X8

    UniProtKB/TrEMBL
    F1M3J3

  15. XM_008760649.4 → XP_008758871.2  single-stranded DNA-binding protein 2 isoform X9

    UniProtKB/TrEMBL
    F1M3J3
    Related
    ENSRNOP00000021857.8, ENSRNOT00000021857.10

  16. XM_063282009.1 → XP_063138079.1  single-stranded DNA-binding protein 2 isoform X14

  17. XM_063282010.1 → XP_063138080.1  single-stranded DNA-binding protein 2 isoform X16

  18. XM_063282011.1 → XP_063138081.1  single-stranded DNA-binding protein 2 isoform X17

  19. XM_008760653.4 → XP_008758875.2  single-stranded DNA-binding protein 2 isoform X18

  20. XM_039103432.2 → XP_038959360.1  single-stranded DNA-binding protein 2 isoform X15

    UniProtKB/TrEMBL
    F1M3J3
    Conserved Domains (1) summary
    pfam04503
    Location:116 → 380
    SSDP; Single-stranded DNA binding protein, SSDP

  21. XM_039103433.2 → XP_038959361.1  single-stranded DNA-binding protein 2 isoform X19

    UniProtKB/TrEMBL
    F1M3J3
    Conserved Domains (1) summary
    pfam04503
    Location:105 → 369
    SSDP; Single-stranded DNA binding protein, SSDP

  22. XM_039103434.2 → XP_038959362.1  single-stranded DNA-binding protein 2 isoform X21

    UniProtKB/TrEMBL
    A0A8I6AA81
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:99 → 363
    SSDP; Single-stranded DNA binding protein, SSDP

  23. XM_039103447.2 → XP_038959375.1  single-stranded DNA-binding protein 2 isoform X31

    Conserved Domains (1) summary
    pfam04503
    Location:19 → 272
    SSDP; Single-stranded DNA binding protein, SSDP

  24. XM_063282015.1 → XP_063138085.1  single-stranded DNA-binding protein 2 isoform X25

  25. XM_063282016.1 → XP_063138086.1  single-stranded DNA-binding protein 2 isoform X27

    UniProtKB/TrEMBL
    A0A8I6AA81

  26. XM_039103436.2 → XP_038959364.1  single-stranded DNA-binding protein 2 isoform X22

    UniProtKB/TrEMBL
    A0A8I6AA81
    Related
    ENSRNOP00000105179.1, ENSRNOT00000135516.1
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:83 → 347
    SSDP; Single-stranded DNA binding protein, SSDP

  27. XM_039103442.2 → XP_038959370.1  single-stranded DNA-binding protein 2 isoform X28

    UniProtKB/TrEMBL
    A0A8I6AA81, A0A8I6AH80
    Conserved Domains (2) summary
    smart00667
    Location:19 → 45
    LisH; Lissencephaly type-1-like homology motif
    pfam04503
    Location:92 → 316
    SSDP; Single-stranded DNA binding protein, SSDP

  28. XM_063282012.1 → XP_063138082.1  single-stranded DNA-binding protein 2 isoform X20

    UniProtKB/TrEMBL
    F1M3J3

  29. XM_063282017.1 → XP_063138087.1  single-stranded DNA-binding protein 2 isoform X29

    UniProtKB/TrEMBL
    F1M3J3

  30. XM_063282014.1 → XP_063138084.1  single-stranded DNA-binding protein 2 isoform X24

    UniProtKB/TrEMBL
    A0A8I6AA81

  31. XM_063282013.1 → XP_063138083.1  single-stranded DNA-binding protein 2 isoform X23

    UniProtKB/TrEMBL
    F1M3J3

  32. XM_063282019.1 → XP_063138089.1  single-stranded DNA-binding protein 2 isoform X32

  33. XM_063282021.1 → XP_063138091.1  single-stranded DNA-binding protein 2 isoform X34

    UniProtKB/TrEMBL
    A6I4P6

  34. XM_063282024.1 → XP_063138094.1  single-stranded DNA-binding protein 2 isoform X35

    UniProtKB/TrEMBL
    A6I4P7

  35. XM_063282002.1 → XP_063138072.1  single-stranded DNA-binding protein 2 isoform X1

  36. XM_063282018.1 → XP_063138088.1  single-stranded DNA-binding protein 2 isoform X31

  37. XM_039103440.2 → XP_038959368.1  single-stranded DNA-binding protein 2 isoform X26

    UniProtKB/TrEMBL
    F1M3J3
    Conserved Domains (1) summary
    pfam04503
    Location:56 → 320
    SSDP; Single-stranded DNA binding protein, SSDP

  38. XM_039103445.2 → XP_038959373.1  single-stranded DNA-binding protein 2 isoform X30

    UniProtKB/TrEMBL
    F1M3J3
    Conserved Domains (1) summary
    pfam04503
    Location:40 → 304
    SSDP; Single-stranded DNA binding protein, SSDP

  39. XM_039103449.2 → XP_038959377.1  single-stranded DNA-binding protein 2 isoform X31

    Conserved Domains (1) summary
    pfam04503
    Location:19 → 272
    SSDP; Single-stranded DNA binding protein, SSDP

  40. XM_063282023.1 → XP_063138093.1  single-stranded DNA-binding protein 2 isoform X34

    UniProtKB/TrEMBL
    A6I4P6

  41. XM_063282025.1 → XP_063138095.1  single-stranded DNA-binding protein 2 isoform X35

    UniProtKB/TrEMBL
    A6I4P7
Nucleotide Protein Strain
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