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Atp6ap1l ATPase H+ transporting accessory protein 1 like [ Rattus norvegicus (Norway rat) ]

Gene ID: 361875, updated on 4-Jan-2025

Summary

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Official Symbol
Atp6ap1lprovided by RGD
Official Full Name
ATPase H+ transporting accessory protein 1 likeprovided by RGD
Primary source
RGD:1564936
See related
EnsemblRapid:ENSRNOG00000040201 AllianceGenome:RGD:1564936
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564936
Summary
Predicted to enable ATPase activator activity. Predicted to be involved in regulation of cellular pH. Predicted to be part of proton-transporting V-type ATPase complex. Orthologous to human ATP6AP1L (ATPase H+ transporting accessory protein 1 like (pseudogene)). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 105.2), Testes (RPKM 80.6) and 4 other tissues See more
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Genomic context

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See Atp6ap1l in Genome Data Viewer
Location:
2q12
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (23772724..23814913, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (22037542..22079376, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (19781375..19809355, complement)

Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U109 Neighboring gene transmembrane protein 167A Neighboring gene uncharacterized LOC134485712 Neighboring gene ribosomal protein S23 Neighboring gene autophagy related 10 Neighboring gene uncharacterized LOC120100664 Neighboring gene uncharacterized LOC134485814

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of cellular pH IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of proton-transporting V-type ATPase complex IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
V-type proton ATPase subunit S1-like protein
Names
ATPase, H+ transporting, lysosomal accessory protein 1-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191843.1 → NP_001178772.1  V-type proton ATPase subunit S1-like protein precursor

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000002
    UniProtKB/TrEMBL
    D3ZA00
    Related
    ENSRNOP00000050073.4, ENSRNOT00000044237.6
    Conserved Domains (1) summary
    pfam05827
    Location:153 → 293
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086020.1 Reference GRCr8

    Range
    23772724..23814913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102521.2 → XP_038958449.1  V-type proton ATPase subunit S1-like protein isoform X3

    Related
    ENSRNOP00000111706.1, ENSRNOT00000146394.1
    Conserved Domains (1) summary
    pfam05827
    Location:159 → 299
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  2. XM_039102515.2 → XP_038958443.1  V-type proton ATPase subunit S1-like protein isoform X1

    Related
    ENSRNOP00000103211.1, ENSRNOT00000127775.1
    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  3. XM_039102518.1 → XP_038958446.1  V-type proton ATPase subunit S1-like protein isoform X1

    Related
    ENSRNOP00000108078.1, ENSRNOT00000144554.1
    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  4. XM_039102512.2 → XP_038958440.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  5. XM_063282000.1 → XP_063138070.1  V-type proton ATPase subunit S1-like protein isoform X1

  6. XM_063282001.1 → XP_063138071.1  V-type proton ATPase subunit S1-like protein isoform X2

  7. XM_039102516.2 → XP_038958444.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  8. XM_039102513.2 → XP_038958441.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  9. XM_039102517.2 → XP_038958445.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  10. XM_039102510.2 → XP_038958438.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  11. XM_063281999.1 → XP_063138069.1  V-type proton ATPase subunit S1-like protein isoform X1

  12. XM_039102511.2 → XP_038958439.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  13. XM_039102522.2 → XP_038958450.1  V-type proton ATPase subunit S1-like protein isoform X4

    UniProtKB/TrEMBL
    D3ZA00
    Conserved Domains (1) summary
    pfam05827
    Location:153 → 293
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  14. XM_039102520.2 → XP_038958448.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)

  15. XM_039102514.2 → XP_038958442.1  V-type proton ATPase subunit S1-like protein isoform X1

    Conserved Domains (1) summary
    pfam05827
    Location:161 → 301
    ATP-synt_S1; Vacuolar ATP synthase subunit S1 (ATP6S1)
Nucleotide Protein Strain
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