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Tulp2 TUB like protein 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361576, updated on 14-Nov-2024

Summary

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Official Symbol
Tulp2provided by RGD
Official Full Name
TUB like protein 2provided by RGD
Primary source
RGD:1310551
See related
EnsemblRapid:ENSRNOG00000020927 AllianceGenome:RGD:1310551
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in protein localization to cilium. Predicted to be located in extracellular region. Predicted to be active in cilium. Orthologous to human TULP2 (TUB like protein 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Restricted expression toward (RPKM 913.5) See more
Orthologs
human mouse all
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Genomic context

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See Tulp2 in Genome Data Viewer
Location:
1q22
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (105098884..105136243)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (95962496..95999775)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (101474334..101511621)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene ferritin light chain 1 Neighboring gene BCL2 associated X, apoptosis regulator Neighboring gene dihydrodiol dehydrogenase Neighboring gene nucleobindin 1 Neighboring gene protein phosphatase 1, regulatory subunit 15A Neighboring gene pleckstrin homology domain containing A4 Neighboring gene transfer RNA serine (anticodon AGA) 17

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Mukhopadhyay S, et al. Genes Dev, 2010 Oct 1. PMID 20889716, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in protein localization to cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cilium IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tubby-related protein 2
Names
tubby-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012168.1 → NP_001012168.1  tubby-related protein 2

    See identical proteins and their annotated locations for NP_001012168.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084696
    UniProtKB/TrEMBL
    A0A8I6G891, Q5XFX6
    Conserved Domains (2) summary
    pfam01167
    Location:232 → 479
    Tub; Tub family
    pfam16322
    Location:13 → 167
    Tub_N; Tubby N-terminal

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    105098884..105136243
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063266801.1 → XP_063122871.1  tubby-related protein 2 isoform X8

  2. XM_006229103.5 → XP_006229165.2  tubby-related protein 2 isoform X2

    UniProtKB/TrEMBL
    A6JB47
    Related
    ENSRNOP00000082997.2, ENSRNOT00000118962.2

  3. XM_063266742.1 → XP_063122812.1  tubby-related protein 2 isoform X1

    Related
    ENSRNOP00000062682.3, ENSRNOT00000064245.4

  4. XM_063266753.1 → XP_063122823.1  tubby-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0G2K250

  5. XM_063266764.1 → XP_063122834.1  tubby-related protein 2 isoform X4

  6. XM_063266786.1 → XP_063122856.1  tubby-related protein 2 isoform X6

  7. XM_006229106.4 → XP_006229168.1  tubby-related protein 2 isoform X7

    UniProtKB/TrEMBL
    A6JB47
    Conserved Domains (2) summary
    pfam01167
    Location:252 → 499
    Tub; Tub family
    pfam16322
    Location:1 → 187
    Tub_N; Tubby N-terminal

  8. XM_017589366.3 → XP_017444855.1  tubby-related protein 2 isoform X9

    UniProtKB/TrEMBL
    A0A8I6G891
    Conserved Domains (2) summary
    pfam01167
    Location:196 → 443
    Tub; Tub family
    pfam16322
    Location:5 → 131
    Tub_N; Tubby N-terminal

  9. XM_063266775.1 → XP_063122845.1  tubby-related protein 2 isoform X5

  10. XM_008759398.4 → XP_008757620.1  tubby-related protein 2 isoform X9

    See identical proteins and their annotated locations for XP_008757620.1

    UniProtKB/TrEMBL
    A0A8I6G891
    Conserved Domains (2) summary
    pfam01167
    Location:196 → 443
    Tub; Tub family
    pfam16322
    Location:5 → 131
    Tub_N; Tubby N-terminal

  11. XM_063266811.1 → XP_063122881.1  tubby-related protein 2 isoform X10

Nucleotide Protein Strain
Heading Accession and Version

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