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CG7222 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36138, updated on 9-Dec-2024

Summary

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Official Symbol
CG7222provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033551
Locus tag
Dmel_CG7222
See related
AllianceGenome:FB:FBgn0033551
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG7222
Summary
Predicted to enable cysteine-type deubiquitinase activity. Is expressed in adult head and organism. Orthologous to human DESI2 (desumoylating isopeptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG7222 in Genome Data Viewer
Location:
47C1-47C1; 2-63 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10813405..10815781)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6700910..6703286)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Nop10 ribonucleoprotein Neighboring gene Methyl methanesulfonate sensitivity 4 Neighboring gene uncharacterized protein Neighboring gene diego Neighboring gene Proteasome beta5 subunit Neighboring gene Lsm10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Model system identification of novel congenital heart disease gene candidates: focus on RPL13. Schroeder AM, et al. Hum Mol Genet, 2019 Dec 1. PMID 31625562, Free PMC Article
  2. Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila. Caizzi R, et al. PLoS Genet, 2016 Aug. PMID 27513559, Free PMC Article
  3. An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination. Kanca O, et al. Elife, 2022 Jun 20. PMID 35723254, Free PMC Article
  4. Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis. Lin WH, et al. Dis Model Mech, 2017 Feb 1. PMID 28067623, Free PMC Article
  5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables deubiquitinase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG7222-PA
CG7222-PB
NP_001286295.1
NP_610613.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10813405..10815781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299366.1 → NP_001286295.1  uncharacterized protein Dmel_CG7222, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286295.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K2B1
    Conserved Domains (1) summary
    pfam05903
    Location:37 → 181
    Peptidase_C97; PPPDE putative peptidase domain

  2. NM_136769.3 → NP_610613.1  uncharacterized protein Dmel_CG7222, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610613.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K2B1
    Related
    FBpp0087318
    Conserved Domains (1) summary
    pfam05903
    Location:37 → 181
    Peptidase_C97; PPPDE putative peptidase domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K2B1 Q7K2B1

Gene LinkOut

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