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Cyp49a1 - Cytochrome P450 49a1

Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in several structures, including cercus; embryonic anal pad; embryonic epipharynx; embryonic head; and gut section. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bone disease (multiple); cerebrotendinous xanthomatosis; gastrointestinal system cancer (multiple); and lung cancer (multiple). Orthologous to human CYP24A1 (cytochrome P450 family 24 subfamily A member 1); CYP27A1 (cytochrome P450 family 27 subfamily A member 1); and CYP27B1 (cytochrome P450 family 27 subfamily B member 1). [provided by Alliance of Genome Resources, Nov 2024]

NCBI Orthologs

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Species Gene Architecture aa