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Armh4 armadillo-like helical domain containing 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 361032, updated on 27-Nov-2024

Summary

Official Symbol
Armh4provided by RGD
Official Full Name
armadillo-like helical domain containing 4provided by RGD
Primary source
RGD:1310110
See related
EnsemblRapid:ENSRNOG00000031849 AllianceGenome:RGD:1310110
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310110
Summary
Predicted to enable TORC2 complex binding activity. Predicted to be involved in regulation of TORC2 signaling and regulation of inflammatory response. Predicted to be located in membrane. Orthologous to human ARMH4 (armadillo like helical domain containing 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Brain (RPKM 146.6), Kidney (RPKM 16.8) and 7 other tissues See more
Orthologs
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Genomic context

See Armh4 in Genome Data Viewer
Location:
15p14
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (25455478..25556569, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (22975895..23076986, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (26586359..26687412, complement)

Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 198 Neighboring gene solute carrier family 35, member F4 Neighboring gene uncharacterized LOC102556222 Neighboring gene transcription initiation factor IIA subunit 2-like Neighboring gene outer dynein arm docking complex subunit 2, pseudogene 1 Neighboring gene olfactory receptor family 4 subfamily N member 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables TORC2 complex binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in regulation of TORC2 signaling ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of inflammatory response ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
armadillo-like helical domain-containing protein 4
Names
uncharacterized protein C14orf37 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001108374.1NP_001101844.1  armadillo-like helical domain-containing protein 4

    See identical proteins and their annotated locations for NP_001101844.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474040
    UniProtKB/TrEMBL
    A0A8I6GIE0, A6KE89, D3ZYI3
    Related
    ENSRNOP00000051182.6, ENSRNOT00000041420.7
    Conserved Domains (1) summary
    pfam15767
    Location:48599
    DUF4696; Domain of unknown function (DUF4696)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086033.1 Reference GRCr8

    Range
    25455478..25556569 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039093475.1XP_038949403.1  armadillo-like helical domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A8I6GIE0
    Related
    ENSRNOP00000089792.2, ENSRNOT00000106281.2
    Conserved Domains (1) summary
    pfam15767
    Location:48602
    DUF4696; Domain of unknown function (DUF4696)