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Syb - Synaptobrevin

Enables SNARE binding activity. Involved in positive regulation of vesicle fusion and vesicle fusion. Predicted to be located in synaptic vesicle. Predicted to be part of SNARE complex. Predicted to be active in plasma membrane. Is expressed in several structures, including Malpighian tubule primordium; adult digestive system; adult head; adult heart; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome and spastic ataxia 1. Orthologous to human VAMP1 (vesicle associated membrane protein 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa