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Pfk - Phosphofructokinase

Enables 6-phosphofructokinase activity. Involved in several processes, including fructose 1,6-bisphosphate metabolic process; fructose 6-phosphate metabolic process; and glycolytic process. Predicted to be located in cytosol and mitochondrion. Predicted to be part of 6-phosphofructokinase complex. Is expressed in several structures, including adult head; adult heart; larval muscle system; muscle cell; and spermatozoon. Used to study disease of metabolism. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Orthologous to several human genes including PFKL (phosphofructokinase, liver type) and PFKM (phosphofructokinase, muscle). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa