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RpLP0-like Ribosomal protein LP0-like [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36058, updated on 9-Dec-2024

Summary

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Official Symbol
RpLP0-likeprovided by FlyBase
Official Full Name
Ribosomal protein LP0-likeprovided by FlyBase
Primary source
FLYBASE:FBgn0033485
Locus tag
Dmel_CG1381
See related
AllianceGenome:FB:FBgn0033485
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1381; Dmel\CG1381; MRT4
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in nuclear-transcribed mRNA catabolic process; rRNA processing; and ribosomal large subunit biogenesis. Predicted to be part of cytosolic large ribosomal subunit and preribosome, large subunit precursor. Predicted to be active in nucleolus. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; larval muscle system; larval somatic muscle cell; and mesoderm. Orthologous to human MRTO4 (MRT4 homolog, ribosome maturation factor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See RpLP0-like in Genome Data Viewer
Location:
46E5-46E6; 2-62 cM
Exon count:
3
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10098518..10099590, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5986023..5987095, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene snoRNA:Orphan C/D box 13 Neighboring gene eiger Neighboring gene uncharacterized protein Neighboring gene sugar transporter 4 Neighboring gene 14-3-3zeta Neighboring gene Jun-related antigen Neighboring gene Phosphofructokinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes. van der Knaap JA, et al. Mol Cell Biol, 2010 Feb. PMID 19995917, Free PMC Article
  2. Upregulation of ribosome biogenesis via canonical E-boxes is required for Myc-driven proliferation. Zielke N, et al. Dev Cell, 2022 Apr 25. PMID 35472319
  3. Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila. Demontis F, et al. Development, 2009 Mar. PMID 19211682, Free PMC Article
  4. Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila. Pasquier C, et al. Life Sci Alliance, 2022 Feb. PMID 34844981, Free PMC Article
  5. Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching. Hopes T, et al. Nucleic Acids Res, 2022 Feb 28. PMID 34283226, Free PMC Article

See all (40) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of ribosome TAS
Traceable Author Statement
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoplasmic translation TAS
Traceable Author Statement
more info
 PubMed 
involved_in nuclear-transcribed mRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ribosomal large subunit assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal large subunit biogenesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in translation IC
Inferred by Curator
more info
  
Component Evidence Code Pubs
part_of cytosolic large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of cytosolic large ribosomal subunit TAS
Traceable Author Statement
more info
 PubMed 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of preribosome, large subunit precursor IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ribosomal protein LP0-like
Names
CG1381-PA
RpLP0-like-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    10098518..10099590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136710.4 → NP_610554.1  ribosomal protein LP0-like [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610554.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K1Q7
    Related
    FBpp0087511
    Conserved Domains (1) summary
    cd05796
    Location:21 → 184
    Ribosomal_P0_like; Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0, including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K1Q7 Q7K1Q7

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