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Marc Mitochondrial amidoxime reducing component [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36014, updated on 4-Jan-2025

Summary

Official Symbol
Marcprovided by FlyBase
Official Full Name
Mitochondrial amidoxime reducing componentprovided by FlyBase
Primary source
FLYBASE:FBgn0033451
Locus tag
Dmel_CG1665
See related
AllianceGenome:FB:FBgn0033451
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG1665; Dmel\CG1665; IP19920p; mArc
Summary
Predicted to enable nitrite reductase activity. Predicted to contribute to nitrite reductase (NO-forming) activity. Predicted to be involved in cellular detoxification of nitrogen compound and nitric oxide biosynthetic process. Predicted to be located in mitochondrion. Predicted to be part of nitric-oxide synthase complex. Is expressed in adult head; adult heart; and organism. Orthologous to human MTARC1 (mitochondrial amidoxime reducing component 1) and MTARC2 (mitochondrial amidoxime reducing component 2). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Marc in Genome Data Viewer
Location:
46B4-46B4; 2-61 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9839776..9841163)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5727281..5728668)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene hebe Neighboring gene uncharacterized protein Neighboring gene Lsm11 Neighboring gene Vesicle-associated membrane protein 7 Neighboring gene sting Neighboring gene Proteasome alpha7 subunit Neighboring gene Origin recognition complex subunit 6

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables molybdenum ion binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to nitrite reductase (NO-forming) activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables nitrite reductase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables oxidoreductase activity, acting on other nitrogenous compounds as donors ISS
Inferred from Sequence or Structural Similarity
more info
 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in cellular detoxification of nitrogen compound ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in nitric oxide biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of nitric-oxide synthase complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
mitochondrial amidoxime reducing component
Names
CG1665-PA
Marc-PA
NP_610523.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    9839776..9841163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136679.5NP_610523.2  mitochondrial amidoxime reducing component [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610523.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z803, Q8SXE5
    Related
    FBpp0087562
    Conserved Domains (3) summary
    COG3217
    Location:52337
    YcbX; Uncharacterized conserved protein YcbX, contains MOSC and Fe-S domains [General function prediction only]
    pfam03473
    Location:219336
    MOSC; MOSC domain
    pfam03476
    Location:50172
    MOSC_N; MOSC N-terminal beta barrel domain