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Lsm11 Lsm11 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 36013, updated on 4-Jan-2025

Summary

Official Symbol
Lsm11provided by FlyBase
Official Full Name
Lsm11provided by FlyBase
Primary source
FLYBASE:FBgn0033450
Locus tag
Dmel_CG12924
See related
AllianceGenome:FB:FBgn0033450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG12924; dLsm11; DLsm11; Dmel\CG12924; LSM11
Summary
Predicted to enable U7 snRNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Located in histone locus body. Part of cytoplasmic U snRNP body and histone pre-mRNA 3'end processing complex. Is expressed in female germline cell. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome. Orthologous to human LSM11 (LSM11, U7 small nuclear RNA associated). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Lsm11 in Genome Data Viewer
Location:
46B4-46B4; 2-61 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (9838434..9839500, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (5725939..5727005, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene dilatory Neighboring gene hebe Neighboring gene uncharacterized protein Neighboring gene Mitochondrial amidoxime reducing component Neighboring gene Vesicle-associated membrane protein 7 Neighboring gene sting Neighboring gene Origin recognition complex subunit 6

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
Lsm11
Names
CG12924-PA
Lsm11-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    9838434..9839500 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136678.3NP_610522.1  Lsm11 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610522.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A1Z802, Q8MRZ3
    Related
    FBpp0087569
    Conserved Domains (2) summary
    cd01739
    Location:158204
    LSm11_M; Like-Sm protein 11, middle domain
    cl00259
    Location:166252
    Sm_like; Sm and related proteins