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Obp44a Odorant-binding protein 44a [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35789, updated on 9-Dec-2024

Summary

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Official Symbol
Obp44aprovided by FlyBase
Official Full Name
Odorant-binding protein 44aprovided by FlyBase
Primary source
FLYBASE:FBgn0033268
Locus tag
Dmel_CG2297
See related
AllianceGenome:FB:FBgn0033268
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
44a; anon-EST:ParkEST107; bs11e05.y1; CG2297; DmelObp44a; Dmel\CG2297; obp44a
Summary
Predicted to enable odorant binding activity. Predicted to be involved in sensory perception of smell. Located in extracellular region. Is expressed in several structures, including adult head; adult heart; embryonic central brain neurons; ganglia; and larval nervous system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See Obp44a in Genome Data Viewer
Location:
44B3-44B3; 2-58 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8134170..8135315, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4021675..4022820, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Nucleoporin 50kD Neighboring gene coilin Neighboring gene Suppressor of Cytokine Signaling at 44A Neighboring gene uncharacterized protein Neighboring gene PSEA-binding protein 49kD Neighboring gene Pabp2 Neighboring gene Lipin Neighboring gene kermit Neighboring gene long non-coding RNA:CR44068 Neighboring gene pseudo

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression and purification of Drosophila OBP44a with the aids of LC-MS and NMR. He Y, et al. Protein Expr Purif, 2023 Dec. PMID 37597794, Free PMC Article
  2. Diverse biological processes coordinate the transcriptional response to nutritional changes in a Drosophila melanogaster multiparent population. Ng'oma E, et al. BMC Genomics, 2020 Jan 28. PMID 31992183, Free PMC Article
  3. Proteome profiling reveals tissue-specific protein expression in the male reproductive system of Drosophila melanogaster. Yamamoto MT, et al. Fly (Austin), 2010 Jan-Mar. PMID 20139713
  4. Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster. Cridland JM, et al. Genetics, 2023 May 4. PMID 36869688, Free PMC Article
  5. Stochastic Modeling of Gene Expression Evolution Uncovers Tissue- and Sex-Specific Properties of Expression Evolution in the Drosophila Genus. Pal S, et al. J Comput Biol, 2023 Jan. PMID 36037023, Free PMC Article

See all (60) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables odorant binding IEA
Inferred from Electronic Annotation
more info
  
enables odorant binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in sensory perception of chemical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular region HDA PubMed 
located_in extracellular region ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
Odorant-binding protein 44a
Names
CG2297-PA
CG2297-PB
Obp44a-PA
Obp44a-PB
odorant-binding protein 44a

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8134170..8135315 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299257.1 → NP_001286186.1  Odorant-binding protein 44a, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286186.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K084
    Conserved Domains (1) summary
    smart00708
    Location:32 → 132
    PhBP; Insect pheromone/odorant binding protein domains

  2. NM_136514.4 → NP_610358.1  Odorant-binding protein 44a, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610358.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q7K084
    Related
    FBpp0087892
    Conserved Domains (1) summary
    smart00708
    Location:32 → 132
    PhBP; Insect pheromone/odorant binding protein domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7K084 Q7K084

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