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slv saliva [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35773, updated on 4-Jan-2025

Summary

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Official Symbol
slvprovided by FlyBase
Official Full Name
salivaprovided by FlyBase
Primary source
FLYBASE:FBgn0025469
Locus tag
Dmel_CG8717
See related
AllianceGenome:FB:FBgn0025469
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG8717; Dmel\CG8717
Summary
Predicted to enable sugar transmembrane transporter activity. Involved in salivary gland development. Predicted to be active in membrane. Is expressed in adult fat body; embryonic/larval salivary gland body; and salivary gland body primordium. Orthologous to human SLC50A1 (solute carrier family 50 member 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See slv in Genome Data Viewer
Location:
44A4-44A4; 2-58 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8080559..8083357, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3968064..3970862, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene lingerer Neighboring gene Vacuolar protein sorting 28 Neighboring gene sugar transporter 1 Neighboring gene sugar transporter 2 Neighboring gene sugar transporter 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A glucose-sensing neuron pair regulates insulin and glucagon in Drosophila. Oh Y, et al. Nature, 2019 Oct. PMID 31645735, Free PMC Article
  2. Gain-of-function screen identifies a role of the Src64 oncogene in Drosophila mushroom body development. Nicolaï M, et al. J Neurobiol, 2003 Dec. PMID 14608664
  3. An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila. Tsuda L, et al. EMBO J, 2006 Jul 12. PMID 16763555, Free PMC Article
  4. Parallel genetic and proteomic screens identify Msps as a CLASP-Abl pathway interactor in Drosophila. Lowery LA, et al. Genetics, 2010 Aug. PMID 20498300, Free PMC Article
  5. Identification of genes that influence gurken expression. Geng C, et al. Fly (Austin), 2007 Sep-Oct. PMID 18836312

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sugar transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sugar transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables sugar transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in carbohydrate transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in salivary gland development IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
saliva
Names
CG8717-PA
CG8717-PB
CG8717-PC
slv-PA
slv-PB
slv-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    8080559..8083357 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299253.1 → NP_001286182.1  saliva, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286182.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O96879, Q7JVE7
    UniProtKB/TrEMBL
    A0A0B4LET7
    Conserved Domains (1) summary
    pfam03083
    Location:8 → 94
    MtN3_slv; Sugar efflux transporter for intercellular exchange

  2. NM_001273868.2 → NP_001260797.1  saliva, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260797.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O96879, Q7JVE7
    UniProtKB/TrEMBL
    A0A0B4LET7
    Conserved Domains (1) summary
    pfam03083
    Location:8 → 94
    MtN3_slv; Sugar efflux transporter for intercellular exchange

  3. NM_058035.4 → NP_477383.1  saliva, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_477383.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O96879, Q7JVE7
    UniProtKB/TrEMBL
    A0A0B4LET7
    Related
    FBpp0087900
    Conserved Domains (1) summary
    pfam03083
    Location:8 → 94
    MtN3_slv; Sugar efflux transporter for intercellular exchange
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LET7 A0A0B4LET7
Q7JVE7.1 Q7JVE7

Gene LinkOut

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