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tor - torso

Enables transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including negative phototaxis; pole cell fate determination; and regulation of intracellular signal transduction. Located in plasma membrane. Is expressed in several structures, including brain; germarium; germline cell; larval multidendritic class IV neuron; and prothoracic gland. Human ortholog(s) of this gene implicated in several diseases, including arteriovenous malformation; basal ganglia calcification; hematologic cancer (multiple); infantile myofibromatosis; and kidney cancer (multiple). Orthologous to several human genes including TEK (TEK receptor tyrosine kinase); PDGFRA (platelet derived growth factor receptor alpha); and PDGFRB (platelet derived growth factor receptor beta). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa