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CG1603 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35683, updated on 4-Jan-2025

Summary

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Official Symbol
CG1603provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0033185
Locus tag
Dmel_CG1603
See related
AllianceGenome:FB:FBgn0033185
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG1603
Summary
Predicted to enable sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See CG1603 in Genome Data Viewer
Location:
43D1-43D1; 2-56 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7513846..7516390, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3401351..3403895, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene dilute class unconventional myosin Neighboring gene mitochondrial translation elongation factor Tu 2 Neighboring gene az2 Neighboring gene uncharacterized protein Neighboring gene Phosphatidylinositol glycan anchor biosynthesis class G Neighboring gene Origin recognition complex subunit 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. New Drosophila promoter-associated architectural protein Mzfp1 interacts with CP190 and is required for housekeeping gene expression and insulator activity. Sokolov V, et al. Nucleic Acids Res, 2024 Jul 8. PMID 38769058, Free PMC Article
  2. clifford (B.4.1) , an allele of CG1603 , causes tissue overgrowth in the Drosophila melanogaster eye. Nowaskie RR, et al. MicroPubl Biol, 2023. PMID 37680216, Free PMC Article
  3. How Genetics Has Helped Piece Together the MAPK Signaling Pathway. Ashton-Beaucage D, et al. Methods Mol Biol, 2017. PMID 27924555
  4. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2014 Mar. PMID 24643257, Free PMC Article
  5. Identification of novel Drosophila neural precursor genes using a differential embryonic head cDNA screen. Brody T, et al. Mech Dev, 2002 Apr. PMID 11900973

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG1603-PA
CG1603-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    7513846..7516390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273849.1 → NP_001260778.1  uncharacterized protein Dmel_CG1603, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260778.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q1LZ24, Q95TL6
    Conserved Domains (5) summary
    COG5048
    Location:424 → 583
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:478 → 498
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam10545
    Location:202 → 287
    MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
    pfam13465
    Location:490 → 513
    zf-H2C2_2; Zinc-finger double domain
    cl23759
    Location:321 → 408
    GT1; GT1, myb-like, SANT family

  2. NM_136446.3 → NP_610290.2  uncharacterized protein Dmel_CG1603, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610290.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q1LZ24, Q95TL6
    Related
    FBpp0088052
    Conserved Domains (5) summary
    COG5048
    Location:424 → 583
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:478 → 498
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam10545
    Location:202 → 287
    MADF_DNA_bdg; Alcohol dehydrogenase transcription factor Myb/SANT-like
    pfam13465
    Location:490 → 513
    zf-H2C2_2; Zinc-finger double domain
    cl23759
    Location:321 → 408
    GT1; GT1, myb-like, SANT family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1LZ24 Q1LZ24
Q95TL6 Q95TL6

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