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viro-2 WH1 domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 3565684, updated on 9-Dec-2024

Summary

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Official Symbol
viro-2
Official Full Name
WH1 domain-containing protein
Primary source
WormBase:WBGene00015107
Locus tag
CELE_B0280.13
See related
AllianceGenome:WB:WBGene00015107
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be active in cytoplasm. Is expressed in intestinal cell and somatic cell. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See viro-2 in Genome Data Viewer
Location:
chromosome: III
Exon count:
9
Sequence:
Chromosome: III; NC_003281.10 (7128901..7132056)

Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Probable-ribose 5-phosphate isomerase Neighboring gene Uncharacterized protein Neighboring gene Protection of telomeres homolog 1 Neighboring gene putative geranylgeranyl transferase type-2 subunit beta Neighboring gene K Homology domain-containing protein Neighboring gene ncRNA Neighboring gene Putative tyrosine-protein phosphatase B0280.11

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. An Evolutionarily Conserved Pathway Essential for Orsay Virus Infection of Caenorhabditis elegans. Jiang H, et al. mBio, 2017 Sep 5. PMID 28874467, Free PMC Article
  2. The alg-1 Gene Is Necessary for Orsay Virus Replication in Caenorhabditis elegans. Cubillas C, et al. J Virol, 2023 Apr 27. PMID 37017532, Free PMC Article
  3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
WH1 domain-containing protein
NP_741212.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003281.10 Reference assembly

    Range
    7128901..7132056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_171181.7 → NP_741212.2  WH1 domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_741212.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q5WRU4
    Conserved Domains (1) summary
    cl17171
    Location:23 → 133
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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