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ints-3 SOSS complex subunit A homolog [ Caenorhabditis elegans ]

Gene ID: 3565441, updated on 4-Jan-2025

Summary

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Official Symbol
ints-3
Official Full Name
SOSS complex subunit A homolog
Primary source
WormBase:WBGene00022360
Locus tag
CELE_Y92H12A.4
See related
AllianceGenome:WB:WBGene00022360
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to be active in cytoplasm. Orthologous to human INTS3 (integrator complex subunit 3). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

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See ints-3 in Genome Data Viewer
Location:
chromosome: I
Exon count:
17
Sequence:
Chromosome: I; NC_003279.8 (1514755..1540926)

Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Dystrobrevin-1 Neighboring gene tRNA (32-2'-O)-methyltransferase regulator THADA Neighboring gene E3 ubiquitin-protein ligase;HECT-type E3 ubiquitin transferase Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PLP-1 binds nematode double-stranded telomeric DNA. Im SH, et al. Mol Cells, 2005 Oct 31. PMID 16267406
  2. Identification of HMG-5 as a double-stranded telomeric DNA-binding protein in the nematode Caenorhabditis elegans. Im SH, et al. FEBS Lett, 2003 Nov 20. PMID 14623111
  3. Disruption of the Caenorhabditis elegans Integrator complex triggers a non-conventional transcriptional mechanism beyond snRNA genes. Gómez-Orte E, et al. PLoS Genet, 2019 Feb. PMID 30807579, Free PMC Article
  4. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
  5. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by WormBase

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
SOSS complex subunit A homolog
NP_001293423.1
  • Confirmed by transcript evidence
NP_001368442.1
  • Confirmed by transcript evidence
NP_001368443.1
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003279.8 Reference assembly

    Range
    1514755..1540926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001306494.2 → NP_001293423.1  SOSS complex subunit A homolog [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_001293423.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    W6RQY9
    Conserved Domains (1) summary
    pfam10189
    Location:249 → 484
    Ints3; Integrator complex subunit 3

  2. NM_001381223.1 → NP_001368442.1  SOSS complex subunit A homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    W6RY35
    Conserved Domains (1) summary
    pfam10189
    Location:85 → 320
    Ints3; Integrator complex subunit 3

  3. NM_001381224.1 → NP_001368443.1  SOSS complex subunit A homolog [Caenorhabditis elegans]

    Status: REVIEWED

    UniProtKB/TrEMBL
    W6RRX0
    Conserved Domains (1) summary
    pfam10189
    Location:1 → 100
    Ints3; Integrator complex subunit 3

RNA

  1. NR_131345.1 RNA Sequence

    Status: REVIEWED

Nucleotide Protein
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Gene LinkOut

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