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dars-2 Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein [ Caenorhabditis elegans ]

Gene ID: 3565124, updated on 4-Jan-2025

Summary

Official Symbol
dars-2
Official Full Name
Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein
Primary source
WormBase:WBGene00001095
Locus tag
CELE_F10C2.6
See related
AllianceGenome:WB:WBGene00001095
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Caenorhabditis elegans (strain: Bristol N2)
Lineage
Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary
Predicted to enable aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Predicted to be located in cytoplasm. Predicted to be active in mitochondrion. Orthologous to human DARS2 (aspartyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Jan 2025]
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Genomic context

See dars-2 in Genome Data Viewer
Location:
chromosome: V
Exon count:
7
Sequence:
Chromosome: V; NC_003283.11 (12048745..12052181)

Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene DNA polymerase delta catalytic subunit Neighboring gene alpha-1,2-Mannosidase Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene PUM-HD domain-containing protein

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by WormBase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables aspartate-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in aspartyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein
NP_506019.2
  • Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003283.11 Reference assembly

    Range
    12048745..12052181
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_073618.8NP_506019.2  Aminoacyl-transfer RNA synthetases class-II family profile domain-containing protein [Caenorhabditis elegans]

    See identical proteins and their annotated locations for NP_506019.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    P90831
    Conserved Domains (1) summary
    PRK00476
    Location:24591
    aspS; aspartyl-tRNA synthetase; Validated