U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cyp9b2 Cytochrome P450 9b2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35635, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
Cyp9b2provided by FlyBase
Official Full Name
Cytochrome P450 9b2provided by FlyBase
Primary source
FLYBASE:FBgn0015039
Locus tag
Dmel_CG4486
See related
AllianceGenome:FB:FBgn0015039
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
9b2; BEST:GH08116; CG4486; cyp9b2; Cyp9B2; CYP9B2; Dmel\CG4486; P-450; P-450 Cyp9b2; P450
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Is expressed in adult head; embryonic midgut chamber; embryonic/larval Malpighian tubule; embryonic/larval midgut; and embryonic/larval midgut primordium. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A43 (cytochrome P450 family 3 subfamily A member 43). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Cyp9b2 in Genome Data Viewer
Location:
42F2-42F2; 2-55 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7130277..7132139, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3017782..3019644, complement)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene transfer RNA:Threonine-AGT 1-2 Neighboring gene uncharacterized protein Neighboring gene espinas Neighboring gene long non-coding RNA:CR44443 Neighboring gene Cytochrome P450 9b1 Neighboring gene Serpin 43Aa Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Loci Contributing to Boric Acid Toxicity in Two Reference Populations of Drosophila melanogaster. Najarro MA, et al. G3 (Bethesda), 2017 Jun 7. PMID 28592646, Free PMC Article
  2. Cytochrome P450 gene clusters in Drosophila melanogaster. Dunkov BC, et al. Mol Gen Genet, 1996 Jun 12. PMID 8676871
  3. Effects of the adenylate cyclase activator forskolin and its inactive derivative 1,9-dideoxyforskolin on insect cytochrome P-450 dependent steroid hydroxylase activity. Keogh DP, et al. Experientia, 1992 Jan 15. PMID 1737575
  4. Alkaloid metabolism by cytochrome P-450 enzymes in Drosophila melanogaster. Danielson PB, et al. Comp Biochem Physiol B Biochem Mol Biol, 1995 Apr. PMID 7749620
  5. [Ethanol inhibits recombination in somatic cells of gamma-irradiated larvae of Drosophila melanogaster]. Zakharenko LP, et al. Genetika, 1998 Mar. PMID 9589864

See all (56) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
cytochrome P450 9b2
Names
CG4486-PA
Cyp9b2-PA
cytochrome P450
cytochrome P450-9b2
fly plexin a
NP_523646.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    7130277..7132139 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_078922.4 → NP_523646.1  cytochrome P450 9b2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523646.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q24123, Q9V4I1
    Related
    FBpp0088126
    Conserved Domains (1) summary
    cl12078
    Location:37 → 478
    p450; Cytochrome P450
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9V4I1.1 Q9V4I1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Chemical Information
Molecular Biology Databases
Research Materials
Tools