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CCHa2-R CCHamide-2 receptor [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35535, updated on 9-Dec-2024

Summary

Official Symbol
CCHa2-Rprovided by FlyBase
Official Full Name
CCHamide-2 receptorprovided by FlyBase
Primary source
FLYBASE:FBgn0033058
Locus tag
Dmel_CG14593
See related
AllianceGenome:FB:FBgn0033058
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-WO0131005.23; CCH2aR; CCHa2r; CCHa2R; CCHamide-2 R; CG14593; CG14594; Dmel\CG14593
Summary
Enables neuropeptide receptor activity. Involved in neuropeptide signaling pathway. Located in membrane. Is expressed in adult head; embryonic abdominal segment; larval central nervous system; larval insulin secreting cell of pars intercerebralis; and ventral midline of embryo. Orthologous to several human genes including BRS3 (bombesin receptor subtype 3) and GRPR (gastrin releasing peptide receptor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See CCHa2-R in Genome Data Viewer
Location:
42A8-42A9; 2-55 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6050949..6068680)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1938454..1956185)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44130 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44131 Neighboring gene lethal (2) k09848

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables G protein-coupled peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables neuropeptide receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neuropeptide receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables neuropeptide receptor activity ISM
Inferred from Sequence Model
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane ISM
Inferred from Sequence Model
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
CCHamide-2 receptor
Names
CCHa2-R-PA
CCHa2-R-PB
CCHa2-R-PC
CG14593-PA
CG14593-PB
CG14593-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    6050949..6068680
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136355.4NP_610199.2  CCHamide-2 receptor, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610199.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1Z6J7, A9UJU7, E1JGY1, Q4V622
    Conserved Domains (2) summary
    pfam00001
    Location:86349
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:77197
    7tm_4; Olfactory receptor
  2. NM_001369980.1NP_001356958.1  CCHamide-2 receptor, isoform C [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A4P7VJP0
    Conserved Domains (1) summary
    cd15927
    Location:70362
    7tmA_Bombesin_R-like; bombesin receptor subfamily, member of the class A family of seven-transmembrane G protein-coupled receptors
  3. NM_001169589.2NP_001163060.1  CCHamide-2 receptor, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001163060.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q4V622
    Conserved Domains (2) summary
    pfam00001
    Location:86349
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:77197
    7tm_4; Olfactory receptor