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Gp210 Glycoprotein 210 kDa [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35512, updated on 4-Jan-2025

Summary

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Official Symbol
Gp210provided by FlyBase
Official Full Name
Glycoprotein 210 kDaprovided by FlyBase
Primary source
FLYBASE:FBgn0266580
Locus tag
Dmel_CG7897
See related
AllianceGenome:FB:FBgn0266580
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG14467; CG7897; Dm gp210; Dmel\CG7897; dmNUP210; gp188; Gp188; gp210; GP210; gp210[[D]]; lyadi
Summary
Predicted to be involved in nuclear pore organization and protein import into nucleus. Located in cytoplasm. Part of nuclear pore inner ring and nuclear pore nuclear basket. Is expressed in adult head and organism. Orthologous to human NUP210 (nucleoporin 210) and NUP210L (nucleoporin 210 like). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See Gp210 in Genome Data Viewer
Location:
41F9-41F10; 2-55 cM
Exon count:
19
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5760862..5774324)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1648367..1661829)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene lethal (2) 09851 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small Cajal body-specific RNA : PsiU2-35.45 Neighboring gene Zinc transporter 41F Neighboring gene Odorant receptor 42a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A 174-kilodalton ATPase/dATPase polypeptide and a glycoprotein of apparently identical molecular weight are common but distinct components of higher eukaryotic nuclear structural protein subfractions. Berrios M, et al. J Biol Chem, 1983 Nov 10. PMID 6138358
  2. Isolation and characterization of a proteinaceous subnuclear fraction composed of nuclear matrix, peripheral lamina, and nuclear pore complexes from embryos of Drosophila melanogaster. Fisher PA, et al. J Cell Biol, 1982 Mar. PMID 6177701, Free PMC Article
  3. Drosophila gp210, an invertebrate nuclear pore complex glycoprotein. Berrios M, et al. Eur J Cell Biol, 1995 May. PMID 7641726
  4. Monoclonal antibodies prepared against the major Drosophila nuclear Matrix-pore complex-lamina glycoprotein bind specifically to the nuclear envelope in situ. Filson AJ, et al. J Biol Chem, 1985 Mar 10. PMID 3919018
  5. Persistence of major nuclear envelope antigens in an envelope-like structure during mitosis in Drosophila melanogaster embryos. Harel A, et al. J Cell Sci, 1989 Nov. PMID 2517292

See all (53) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

mobile_element

  • Loc: 5762348-5762424 mobile_element_type = transposon:FB{}5683
  • Loc: 5773609-5773811 mobile_element_type = transposon:INE-1{}5624

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in nuclear pore organization ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein import into nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear pore IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of nuclear pore IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear pore inner ring IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear pore nuclear basket IDA
Inferred from Direct Assay
more info
 PubMed 
part_of nuclear pore transmembrane ring ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
glycoprotein 210 kDa
Names
CG7897-PA
CG7897-PB
Gp210 ortholog
Gp210-PA
Gp210-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5760862..5774324
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273785.1 → NP_001260714.1  glycoprotein 210 kDa, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260714.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1Z6H7, Q6NP18, Q9GPI0

  2. NM_136340.3 → NP_610184.2  glycoprotein 210 kDa, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610184.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A1Z6H7, Q6NP18, Q9GPI0
    Related
    FBpp0085380
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A1Z6H7.1 A1Z6H7

Gene LinkOut

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