U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cndp2 Cytosolic non-specific dipeptidase 2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35507, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
Cndp2provided by FlyBase
Official Full Name
Cytosolic non-specific dipeptidase 2provided by FlyBase
Primary source
FLYBASE:FBgn0287767
Locus tag
Dmel_CG17337
See related
AllianceGenome:FB:FBgn0287767
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
anon-41Fb; CG17337; CN; CNDP; dcndp; dCNDP2; Dip; Dip-A; DipA; Dm52; Dmel\CG17337; Y
Summary
Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Located in cytosol and nucleus. Is expressed in several structures, including adult head; embryonic/larval crystal cell; embryonic/larval midgut primordium; embryonic/larval salivary gland; and gut section. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Cndp2 in Genome Data Viewer
Location:
41F8-41F8; 2-55 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5697872..5700212)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1585377..1587717)

Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene kune-kune Neighboring gene scarface Neighboring gene vulcan Neighboring gene apterous

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Loss of CNDP causes a shorter lifespan and higher sensitivity to oxidative stress in Drosophila melanogaster. Yamakawa-Kobayashi K, et al. Biomed Res, 2020. PMID 32522930
  2. A toolset to study functions of Cytosolic non-specific dipeptidase 2 (CNDP2) using Drosophila as a model organism. Andreyeva EN, et al. BMC Genet, 2019 Mar 18. PMID 30885138, Free PMC Article
  3. Leveraging genomic databases: from an Aedes albopictus mosquito cell line to the malaria vector Anopheles gambiae via the Drosophila genome project. Eccleston ED, et al. Insect Mol Biol, 2002 Apr. PMID 11966884
  4. Peptidases in Drosophila melanogaster. I. Characterization of dipeptidase and leucine aminopeptidase activities. Hall NA. Biochem Genet, 1986 Oct. PMID 3096312
  5. Genetic characterization of dipeptidase activity modifiers in Drosophila melanogaster from natural populations. Hiraizumi K, et al. Biochem Genet, 1988 Dec. PMID 3149467

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables metallodipeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 
located_in extracellular region HDA PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
cytosolic non-specific dipeptidase 2
Names
CG17337-PA
CG17337-PC
Cndp2-PA
Cndp2-PC
Dipeptidase-A
anon-41Fb
carnosinase
carnosine dipeptidase 2
dipeptidase A
transcription unit Y
NP_001286142.1
NP_610181.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033778.4 Reference assembly

    Range
    5697872..5700212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136337.3 → NP_610181.2  cytosolic non-specific dipeptidase 2, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610181.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MT58
    Related
    FBpp0085374
    Conserved Domains (2) summary
    PRK08201
    Location:8 → 475
    PRK08201; hypothetical protein; Provisional
    cd05676
    Location:11 → 478
    M20_dipept_like_CNDP; M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase

  2. NM_001299213.1 → NP_001286142.1  cytosolic non-specific dipeptidase 2, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286142.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0B4LEQ0
    Conserved Domains (2) summary
    cd05676
    Location:1 → 431
    M20_dipept_like_CNDP; M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase
    COG0624
    Location:1 → 431
    ArgE; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase or related deacylase [Amino acid transport and metabolism]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0B4LEQ0 A0A0B4LEQ0
Q8MT58 Q8MT58

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous