U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG2528 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35435, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
CG2528provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032969
Locus tag
Dmel_CG2528
See related
AllianceGenome:FB:FBgn0032969
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG2528; lincRNA.224
Summary
Enables serine hydrolase activity. Predicted to be involved in proteolysis. Predicted to be active in cytosol. Orthologous to human PREP (prolyl endopeptidase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG2528 in Genome Data Viewer
Location:
40D1-40D2; 2-54 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21974749..21992933, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21981480..21992933, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44803 Neighboring gene long non-coding RNA:CR44804 Neighboring gene long non-coding RNA:CR44916 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genetic analysis of dPsa, the Drosophila orthologue of puromycin-sensitive aminopeptidase, suggests redundancy of aminopeptidases. Schulz C, et al. Dev Genes Evol, 2001 Dec. PMID 11819115
  2. Hidden genetic variation shapes the structure of functional elements in Drosophila. Chakraborty M, et al. Nat Genet, 2018 Jan. PMID 29255259, Free PMC Article
  3. Comparative genomics reveals a constant rate of origination and convergent acquisition of functional retrogenes in Drosophila. Bai Y, et al. Genome Biol, 2007. PMID 17233920, Free PMC Article
  4. Parent genes of retrotransposition-generated gene duplicates in Drosophila melanogaster have distinct expression profiles. Langille MG, et al. Genomics, 2007 Sep. PMID 17628393
  5. Genome-wide view of cell fate specification: ladybird acts at multiple levels during diversification of muscle and heart precursors. Junion G, et al. Genes Dev, 2007 Dec 1. PMID 18056427, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

mobile_element

  • Loc: c21990843-21981738 mobile_element_type = transposon:roo{}CG2528[iso-1]

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables oligopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables serine hydrolase activity HDA PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG2528-PE
CG2528-PG
NP_001303334.1
NP_610129.3
  • unusual splice

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    21974749..21992933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001316405.1 → NP_001303334.1  uncharacterized protein Dmel_CG2528, isoform G [Drosophila melanogaster]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A0T7B3Z6, D5SHQ2
    Conserved Domains (2) summary
    pfam00326
    Location:516 → 670
    Peptidase_S9; Prolyl oligopeptidase family
    pfam02897
    Location:28 → 442
    Peptidase_S9_N; Prolyl oligopeptidase, N-terminal beta-propeller domain

  2. NM_136285.3 → NP_610129.3  uncharacterized protein Dmel_CG2528, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610129.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    D5SHQ2, Q9V9P5
    Conserved Domains (2) summary
    pfam00326
    Location:516 → 727
    Peptidase_S9; Prolyl oligopeptidase family
    pfam02897
    Location:28 → 442
    Peptidase_S9_N; Prolyl oligopeptidase, N-terminal beta-propeller domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A0A0T7B3Z6 A0A0T7B3Z6
Q9V9P5 Q9V9P5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools