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Col23a1 collagen type XXIII alpha 1 chain [ Rattus norvegicus (Norway rat) ]

Gene ID: 353303, updated on 27-Nov-2024

Summary

Symbol
Col23a1provided by RGD
Full Name
collagen type XXIII alpha 1 chainprovided by RGD
Primary source
RGD:727898
See related
EnsemblRapid:ENSRNOG00000003349 AllianceGenome:RGD:727898
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables heparin binding activity and identical protein binding activity. Predicted to be involved in extracellular matrix organization. Located in cell surface and extracellular space. Orthologous to human COL23A1 (collagen type XXIII alpha 1 chain). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in Adrenal (RPKM 58.8), Lung (RPKM 55.5) and 8 other tissues See more
Orthologs
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Genomic context

See Col23a1 in Genome Data Viewer
Location:
10q22
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (36050327..36337279)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (35549090..35839152)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (34846618..34934991)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene putative uncharacterized protein MSANTD5 Neighboring gene Myb/SANT DNA binding domain containing 5 Neighboring gene CDC-like kinase 4 Neighboring gene uncharacterized LOC120095095 Neighboring gene uncharacterized LOC134480786 Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene 5-phosphohydroxy-L-lysine phospho-lyase Neighboring gene heterogeneous nuclear ribonucleoprotein A/B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables extracellular matrix structural constituent conferring tensile strength IBA
Inferred from Biological aspect of Ancestor
more info
 
enables heparin binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
part_of collagen trimer IEA
Inferred from Electronic Annotation
more info
 
is_active_in collagen-containing extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
collagen alpha-1(XXIII) chain
Names
alpha 1 type XXIII collagen
collagen XXIII
collagen alpha-1(XXIII) chain-like
collagen, type XXIII, alpha 1
procollagen, type XXIII, alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181636.2NP_853667.1  collagen alpha-1(XXIII) chain

    See identical proteins and their annotated locations for NP_853667.1

    Status: PROVISIONAL

    Source sequence(s)
    AY158896
    UniProtKB/Swiss-Prot
    Q810Y4
    UniProtKB/TrEMBL
    D3ZFT7
    Related
    ENSRNOP00000062298.2, ENSRNOT00000064078.3
    Conserved Domains (1) summary
    pfam01391
    Location:455512
    Collagen; Collagen triple helix repeat (20 copies)

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    36050327..36337279
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)