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IKKepsilon - I-kappaB kinase epsilon

Enables protein serine/threonine kinase activity and small GTPase binding activity. Involved in several processes, including antiviral innate immune response; cell maturation; and cytoskeleton organization. Located in cell tip and cytoplasm. Human ortholog(s) of this gene implicated in brain disease and frontotemporal dementia and/or amyotrophic lateral sclerosis 4. Orthologous to several human genes including IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to IKKepsilon

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Species Gene Architecture aa