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Pyroxd1 Pyridine nucleotide-disulfide oxidoreductase domain 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35296, updated on 9-Dec-2024

Summary

Official Symbol
Pyroxd1provided by FlyBase
Official Full Name
Pyridine nucleotide-disulfide oxidoreductase domain 1provided by FlyBase
Primary source
FLYBASE:FBgn0032846
Locus tag
Dmel_CG10721
See related
AllianceGenome:FB:FBgn0032846
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
38B.14; CG10721; Dmel\CG10721
Summary
Predicted to enable oxidoreductase activity. Human ortholog(s) of this gene implicated in myofibrillar myopathy 8. Orthologous to human PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See Pyroxd1 in Genome Data Viewer
Location:
38B5-38B6; 2-54 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (20091435..20093152)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (20091435..20093152)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene nebbish Neighboring gene fledgling of Klp38B Neighboring gene uncharacterized protein Neighboring gene TBP-associated factor 13 Neighboring gene nessun dorma Neighboring gene mitochondrial ribosomal protein S18B

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
pyridine nucleotide-disulfide oxidoreductase domain 1
Names
CG10721-PA
CG10721-PB
Pyroxd1-PA
Pyroxd1-PB
NP_001260619.1
NP_610023.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    20091435..20093152
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001273690.1NP_001260619.1  pyridine nucleotide-disulfide oxidoreductase domain 1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001260619.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VIP2
    Conserved Domains (1) summary
    pfam07992
    Location:8355
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
  2. NM_136179.3NP_610023.1  pyridine nucleotide-disulfide oxidoreductase domain 1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_610023.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VIP2
    Related
    FBpp0080865
    Conserved Domains (1) summary
    pfam07992
    Location:8355
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase