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CG10631 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35262, updated on 9-Dec-2024

Summary

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Official Symbol
CG10631provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0032817
Locus tag
Dmel_CG10631
See related
AllianceGenome:FB:FBgn0032817
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10631
Summary
Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including anterior endoderm; embryonic/larval midgut primordium; gastric caecum; posterior endoderm; and spermatozoon. Orthologous to human ZNF212 (zinc finger protein 212) and ZNF671 (zinc finger protein 671). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG10631 in Genome Data Viewer
Location:
38A2-38A2; 2-54 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19742817..19756904, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19742817..19756904, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Nuclear factor Y-box B Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Dihydrouridine synthase 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptomic analysis provides insight into the mechanism of IKKβ-mediated suppression of HPV18E6-induced cellular abnormalities. Collins QP, et al. G3 (Bethesda), 2023 Apr 11. PMID 36722216, Free PMC Article
  2. Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila. Bushati N, et al. Curr Biol, 2008 Apr 8. PMID 18394895
  3. Neurological proteins are not enriched for repetitive sequences. Huntley MA, et al. Genetics, 2004 Mar. PMID 15082536, Free PMC Article
  4. A genetic screen and transcript profiling reveal a shared regulatory program for Drosophila linker histone H1 and chromatin remodeler CHD1. Kavi H, et al. G3 (Bethesda), 2015 Jan 27. PMID 25628309, Free PMC Article
  5. Analysis of Ras-induced overproliferation in Drosophila hemocytes. Asha H, et al. Genetics, 2003 Jan. PMID 12586708, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription corepressor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10631-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    19742817..19756904 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_136154.2 → NP_609998.1  uncharacterized protein Dmel_CG10631 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609998.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VIS5
    Related
    FBpp0080856
    Conserved Domains (4) summary
    smart00692
    Location:3396 → 3452
    DM3; Zinc finger domain in CG10631, C. elegans LIN-15B and human P52rIPK
    smart00980
    Location:1424 → 1493
    THAP; The THAP domain is a putative DNA-binding domain (DBD) and probably also binds a zinc ion
    sd00017
    Location:288 → 311
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam05485
    Location:3621 → 3669
    THAP; THAP domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VIS5 Q9VIS5

Gene LinkOut

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