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Ugt36E1 UDP-glycosyltransferase family 36 member E1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35139, updated on 4-Jan-2025

Summary

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Official Symbol
Ugt36E1provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 36 member E1provided by FlyBase
Primary source
FLYBASE:FBgn0027070
Locus tag
Dmel_CG17322
See related
AllianceGenome:FB:FBgn0027070
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BEST:LD25345; CG17322; Dmel\CG17322; LD25345; UGT36E1
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be involved in glycosylation and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Is expressed in adult head; adult heart; and organism. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Ugt36E1 in Genome Data Viewer
Location:
37B1-37B1; 2-54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18826770..18829059)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18826770..18829059)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene UDP-glycosyltransferase family 36 member F1 Neighboring gene UDP-glycosyltransferase family 36 member D1 Neighboring gene uncharacterized protein Neighboring gene Sterol carrier protein X-related thiolase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Modulation of Sex Pheromone Discrimination by A UDP-Glycosyltransferase in Drosophila melanogaster. Fraichard S, et al. Genes (Basel), 2020 Feb 25. PMID 32106439, Free PMC Article
  2. Preferential expression of biotransformation enzymes in the olfactory organs of Drosophila melanogaster, the antennae. Wang Q, et al. J Biol Chem, 1999 Apr 9. PMID 10187818
  3. Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer's disease. Garrido-Maraver J, et al. Biol Open, 2020 Jan 14. PMID 31822473, Free PMC Article
  4. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
  5. Systematic analysis of the visual projection neurons of Drosophila melanogaster. I. Lobula-specific pathways. Otsuna H, et al. J Comp Neurol, 2006 Aug 20. PMID 16802334

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
 PubMed 
involved_in xenobiotic metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
UDP-glycosyltransferase family 36 member E1
Names
CG17322-PA
CG17322-PB
CG17322-PC
CG17322-PD
Ugt36E1-PA
Ugt36E1-PB
Ugt36E1-PC
Ugt36E1-PD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    18826770..18829059
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_165264.3 → NP_724134.1  UDP-glycosyltransferase family 36 member E1, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724134.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T063, Q9VJ45
    Related
    FBpp0080656
    Conserved Domains (1) summary
    PHA03392
    Location:3 → 460
    egt; ecdysteroid UDP-glucosyltransferase; Provisional

  2. NM_136067.4 → NP_609911.1  UDP-glycosyltransferase family 36 member E1, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609911.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T063, Q9VJ45
    Related
    FBpp0080658
    Conserved Domains (1) summary
    PHA03392
    Location:3 → 460
    egt; ecdysteroid UDP-glucosyltransferase; Provisional

  3. NM_165265.3 → NP_724135.1  UDP-glycosyltransferase family 36 member E1, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724135.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T063, Q9VJ45
    Related
    FBpp0080657
    Conserved Domains (1) summary
    PHA03392
    Location:3 → 460
    egt; ecdysteroid UDP-glucosyltransferase; Provisional

  4. NM_165263.3 → NP_724133.1  UDP-glycosyltransferase family 36 member E1, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_724133.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8T063, Q9VJ45
    Related
    FBpp0080655
    Conserved Domains (1) summary
    PHA03392
    Location:3 → 460
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VJ45 Q9VJ45

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