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ham - hamlet

Enables DNA-binding transcription factor activity. Involved in several processes, including neuroblast fate commitment; regulation of DNA-templated transcription; and regulation of dendrite development. Located in nucleus. Is expressed in several structures, including embryonic dorsal sensory organ precursor cluster; embryonic lateral sensory organ precursor cluster; embryonic ventral sensory organ precursor cluster group; presumptive embryonic/larval peripheral nervous system; and somatic precursor cell. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1LL and myeloid neoplasm. Orthologous to several human genes including MECOM (MDS1 and EVI1 complex locus). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa