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Pde11 - Phosphodiesterase 11

Enables 3',5'-cyclic-AMP phosphodiesterase activity and 3',5'-cyclic-GMP phosphodiesterase activity. Involved in cAMP metabolic process and cGMP metabolic process. Located in cytosol. Is expressed in several structures, including Malpighian tubule primordium; adult brain cell body rind; adult gnathal ganglion; embryonic/larval midgut primordium; and synaptic neuropil domain. Human ortholog(s) of this gene implicated in IgA glomerulonephritis. Orthologous to human PDE5A (phosphodiesterase 5A). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa