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ppk17 pickpocket 17 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 35006, updated on 9-Dec-2024

Summary

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Official Symbol
ppk17provided by FlyBase
Official Full Name
pickpocket 17provided by FlyBase
Primary source
FLYBASE:FBgn0032602
Locus tag
Dmel_CG13278
See related
AllianceGenome:FB:FBgn0032602
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG13278; Dmel\CG13278; Ppk17
Summary
Predicted to enable ligand-gated sodium channel activity. Predicted to be involved in sodium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See ppk17 in Genome Data Viewer
Location:
36A14-36A14; 2-52 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16758184..16760554, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16758184..16760554, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Chitin and LDLR binding deacetylase 3 Neighboring gene Like Sm 7 Neighboring gene Bub3 interacting GLEBS and Zinc finger domain protein Neighboring gene yellow-b Neighboring gene Myosin heavy chain Neighboring gene Cytochrome b5-related

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sensory functions for degenerin/epithelial sodium channels (DEG/ENaC). Ben-Shahar Y. Adv Genet, 2011. PMID 22099690, Free PMC Article
  2. Evolution of the Insect PPK Gene Family. Latorre-Estivalis JM, et al. Genome Biol Evol, 2021 Sep 1. PMID 34390578, Free PMC Article
  3. The genetic architecture of degenerin/epithelial sodium channels in Drosophila. Zelle KM, et al. G3 (Bethesda), 2013 Mar. PMID 23449991, Free PMC Article
  4. Identification of potential mechanosensitive ion channels involved in texture discrimination during Drosophila suzukii egg-laying behaviour. Guo L, et al. Insect Mol Biol, 2020 Oct. PMID 32596943
  5. Molecular and cellular basis of sodium sensing in Drosophila labellum. Asefa WR, et al. iScience, 2024 Jul 19. PMID 39015148, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables ligand-gated sodium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables sodium channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in sodium ion transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transport ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
pickpocket 17
Names
CG13278-PA
CG13278-PB
ppk17-PA
ppk17-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16758184..16760554 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299059.1 → NP_001285988.1  pickpocket 17, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285988.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VJI4
    Conserved Domains (1) summary
    cl02990
    Location:11 → 358
    ASC; Amiloride-sensitive sodium channel

  2. NM_135965.2 → NP_609809.1  pickpocket 17, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609809.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VJI4
    Related
    FBpp0080487
    Conserved Domains (1) summary
    cl02990
    Location:11 → 358
    ASC; Amiloride-sensitive sodium channel
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VJI4 Q9VJI4

Gene LinkOut

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