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CG4935 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34955, updated on 9-Dec-2024

Summary

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Official Symbol
CG4935provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0028897
Locus tag
Dmel_CG4935
See related
AllianceGenome:FB:FBgn0028897
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BG:DS02740.2; Dmel\CG4935; MET30
Summary
Predicted to enable molecular adaptor activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in organism. Orthologous to human WDR83 (WD repeat domain 83). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See CG4935 in Genome Data Viewer
Location:
35F1-35F1; 2-52 cM
Exon count:
5
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16262141..16263483)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16262141..16263483)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene PRL-1 phosphatase Neighboring gene Endonuclease G inhibitor Neighboring gene twine Neighboring gene cropped Neighboring gene pkaap

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Neighbourhood continuity is not required for correct testis gene expression in Drosophila. Meadows LA, et al. PLoS Biol, 2010 Nov 30. PMID 21151342, Free PMC Article
  2. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
  3. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
  4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
  5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular adaptor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mRNA splicing, via spliceosome IC
Inferred by Curator
more info
 PubMed 
Component Evidence Code Pubs
part_of catalytic step 2 spliceosome HDA PubMed 
part_of catalytic step 2 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of precatalytic spliceosome HDA PubMed 

General protein information

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Preferred Names
uncharacterized protein
Names
CG4935-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16262141..16263483
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135938.3 → NP_609782.2  uncharacterized protein Dmel_CG4935 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609782.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NK62, Q9VJL9
    Related
    FBpp0080383
    Conserved Domains (3) summary
    COG2319
    Location:10 → 302
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:10 → 281
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:21 → 57
    7WD40; WD40 repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VJL9 Q9VJL9

Gene LinkOut

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