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beat-Ic beaten path Ic [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34945, updated on 9-Dec-2024

Summary

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Official Symbol
beat-Icprovided by FlyBase
Official Full Name
beaten path Icprovided by FlyBase
Primary source
FLYBASE:FBgn0028644
Locus tag
Dmel_CG4838
See related
AllianceGenome:FB:FBgn0028644
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
beat Ic; beat-1c; beat-C; Beat-Ic; BG:DS00913.1; CG4838; CT15531; Dmel\CG4838
Summary
Involved in axon guidance; defasciculation of motor neuron axon; and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in plasma membrane. Is expressed in adult head; lobula columnar neuron LC12; organism; and peripodial epithelium of eye disc. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See beat-Ic in Genome Data Viewer
Location:
35E1-35E2; 2-51 cM
Exon count:
8
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (16000291..16041703)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (16000291..16041703)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43412 Neighboring gene long non-coding RNA:CR43825 Neighboring gene long non-coding RNA:CR43826 Neighboring gene long non-coding RNA:CR44844 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Bicaudal C Neighboring gene beaten path Ia Neighboring gene long non-coding RNA:CR44870

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2. Kim SH, et al. Elife, 2023 Apr 11. PMID 37039476, Free PMC Article
  2. Specification of Drosophila motoneuron identity by the combinatorial action of POU and LIM-HD factors. Certel SJ, et al. Development, 2004 Nov. PMID 15469973
  3. Asymmetric activity of NetrinB controls laterality of the Drosophila brain. Lapraz F, et al. Nat Commun, 2023 Feb 24. PMID 36828820, Free PMC Article
  4. The Beat generation: a multigene family encoding IgSF proteins related to the Beat axon guidance molecule in Drosophila. Pipes GC, et al. Development, 2001 Nov. PMID 11714679
  5. Fine scale structural variants distinguish the genomes of Drosophila melanogaster and D. pseudoobscura. Macdonald SJ, et al. Genome Biol, 2006. PMID 16872532, Free PMC Article

See all (46) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

mobile_element

  • Loc: 16040641-16040682 mobile_element_type = transposon:INE-1{}2856

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in axon guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in defasciculation of motor neuron axon IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in motor neuron axon guidance IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
beaten path Ic
Names
CG4838-PA
CG4838-PB
CG4838-PC
beat-Ic-PA
beat-Ic-PB
beat-Ic-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    16000291..16041703
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001299041.1 → NP_001285970.1  beaten path Ic, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285970.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NK69, Q9VJM4
    Conserved Domains (1) summary
    cl11960
    Location:189 → 246
    Ig; Immunoglobulin domain

  2. NM_001299042.1 → NP_001285971.1  beaten path Ic, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001285971.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NK69, Q9VJM4
    Conserved Domains (1) summary
    cl11960
    Location:189 → 246
    Ig; Immunoglobulin domain

  3. NM_078856.4 → NP_523580.1  beaten path Ic, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_523580.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9NK69, Q9VJM4
    Related
    FBpp0080359
    Conserved Domains (1) summary
    cl11960
    Location:189 → 246
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VJM4 Q9VJM4

Gene LinkOut

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