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NC2beta - Negative Cofactor 2beta

Enables DNA-binding transcription factor binding activity and core promoter sequence-specific DNA binding activity. Involved in chromatin remodeling; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of ATAC complex. Is expressed in several structures, including embryonic dorsal epidermis; embryonic epipharynx; embryonic head epidermis; embryonic hypopharynx; and ganglia. Orthologous to human DR1 (down-regulator of transcription 1). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to NC2beta

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Species Gene Architecture aa