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Vajk2 Vajk2 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34811, updated on 4-Jan-2025

Summary

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Official Symbol
Vajk2provided by FlyBase
Official Full Name
Vajk2provided by FlyBase
Primary source
FLYBASE:FBgn0032538
Locus tag
Dmel_CG16885
See related
AllianceGenome:FB:FBgn0032538
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG16885; CG18634; Dmel\CG16885; vajk-2
Summary
Predicted to enable chitin binding activity. Predicted to be a structural constituent of chitin-based cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be located in chitin-based extracellular matrix. Is expressed in several structures, including adult head; embryonic dorsal epidermis; embryonic epipharynx; embryonic head epidermis; and embryonic hypopharynx. Orthologous to human ZNF512B (zinc finger protein 512B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See Vajk2 in Genome Data Viewer
Location:
34E4-34E4; 2-50 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13932559..13934692, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13932559..13934692, complement)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Ance-3 Neighboring gene Vajk1 Neighboring gene uncharacterized protein Neighboring gene Vajk3 Neighboring gene Nimrod A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila. Cinege G, et al. Insect Biochem Mol Biol, 2017 Aug. PMID 28633893
  2. Small peptides switch the transcriptional activity of Shavenbaby during Drosophila embryogenesis. Kondo T, et al. Science, 2010 Jul 16. PMID 20647469
  3. SoxNeuro and Shavenbaby act cooperatively to shape denticles in the embryonic epidermis of Drosophila. Rizzo NP, et al. Development, 2017 Jun 15. PMID 28506986, Free PMC Article
  4. Candidate genetic modifiers of retinitis pigmentosa identified by exploiting natural variation in Drosophila. Chow CY, et al. Hum Mol Genet, 2016 Feb 15. PMID 26662796, Free PMC Article
  5. Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila. Pasquier C, et al. Life Sci Alliance, 2022 Feb. PMID 34844981, Free PMC Article

See all (35) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables chitin binding ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables structural constituent of chitin-based cuticle ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in chitin-based extracellular matrix ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
Vajk2
Names
CG16885-PA
Vajk2-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    13932559..13934692 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135845.4 → NP_609689.3  Vajk2 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609689.3

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8SZM2, Q9VJV0
    Related
    FBpp0080135
    Conserved Domains (1) summary
    pfam07489
    Location:32 → 97
    Tir_receptor_C; Translocated intimin receptor (Tir) C-terminus
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8SZM2 Q8SZM2

Gene LinkOut

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