ND-B22 NADH dehydrogenase (ubiquinone) B22 subunit [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: ND-B22provided by FlyBase
Official Full Name: NADH dehydrogenase (ubiquinone) B22 subunitprovided by FlyBase
Primary source: FLYBASE:FBgn0032511
Locus tag: Dmel_CG9306
See related: AllianceGenome:FB:FBgn0032511
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG9306; Dmel\CG9306; dNDUFB9; Ndufb9; NDUFB9; NI2M; Q9VJZ4
Summary: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Part of respiratory chain complex I. Is expressed in several structures, including adult head; adult heart; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and gut section. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 24. Orthologous to human NDUFB9 (NADH:ubiquinone oxidoreductase subunit B9). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2L	NT_033779.5 (13370103..13371110, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2L	NT_033779.4 (13370103..13371110, complement)

Chromosome 2L - NT_033779.5 Genomic Context describing neighboring genes

Genomic Sequence:

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Process	Evidence Code	Pubs
involved_in mitochondrial electron transport, NADH to ubiquinone	IC Inferred by Curator more info	PubMed
involved_in mitochondrial electron transport, NADH to ubiquinone	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in mitochondrial inner membrane	IC Inferred by Curator more info	PubMed
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex I	IDA Inferred from Direct Assay more info	PubMed
part_of respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

Names: CG9306-PA; CG9306-PB; NADH ubiquinone oxidoreductase B22; NADH-ubiquinone oxidoreductase B22 subunit; NADH:ubiquinone oxidoreductase B22 subunit; ND-B22-PA; ND-B22-PB

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The following sections contain reference sequences that belong to a specific genome build. Explain