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mRF1 mitochondrial translation release factor 1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 34720, updated on 9-Dec-2024

Summary

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Official Symbol
mRF1provided by FlyBase
Official Full Name
mitochondrial translation release factor 1provided by FlyBase
Primary source
FLYBASE:FBgn0032486
Locus tag
Dmel_CG5705
See related
AllianceGenome:FB:FBgn0032486
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5705; Dmel\CG5705
Summary
Predicted to enable translation release factor activity. Predicted to be involved in mitochondrial translational termination. Predicted to be located in mitochondrion. Is expressed in organism. Orthologous to several human genes including MTRF1L (mitochondrial translation release factor 1 like). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See mRF1 in Genome Data Viewer
Location:
34A10-34A10; 2-47 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (13219979..13221398)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (13219979..13221398)

Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene small nuclear RNA U2 at 34AB b Neighboring gene uncharacterized protein Neighboring gene Ski6 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary. Soshnev AA, et al. Nucleic Acids Res, 2012 Jul. PMID 22406832, Free PMC Article
  2. Extensive use of RNA-binding proteins in Drosophila sensory neuron dendrite morphogenesis. Olesnicky EC, et al. G3 (Bethesda), 2014 Feb 19. PMID 24347626, Free PMC Article
  3. The translation factors of Drosophila melanogaster. Marygold SJ, et al. Fly (Austin), 2017 Jan 2. PMID 27494710, Free PMC Article
  4. Mobile-phone radiation-induced perturbation of gene-expression profiling, redox equilibrium and sporadic-apoptosis control in the ovary of Drosophila melanogaster. Manta AK, et al. Fly (Austin), 2017 Apr 3. PMID 27960592, Free PMC Article
  5. Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network. Orian A, et al. Genes Dev, 2003 May 1. PMID 12695332, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables translation release factor activity IEA
Inferred from Electronic Annotation
more info
  
enables translation release factor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translational termination ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in translational termination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
mitochondrial translation release factor 1
Names
CG5705-PA
mRF1-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033779.5 Reference assembly

    Range
    13219979..13221398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_135773.3 → NP_609617.1  mitochondrial translation release factor 1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_609617.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VK20
    Related
    FBpp0080024
    Conserved Domains (3) summary
    PRK00591
    Location:35 → 378
    prfA; peptide chain release factor 1; Validated
    pfam00472
    Location:234 → 338
    RF-1; RF-1 domain
    pfam03462
    Location:58 → 222
    PCRF; PCRF domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VK20 Q9VK20

Gene LinkOut

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